Considering Tumour Sidedness is Critical for Accurate Interpretation of Liquid Biopsy Results in Metastatic Colorectal Cancer.

Mol Diagn Ther · 2026 · PMC13319506 · PMID 42324399

Europe PMC DOI

hedged sentences

0.0598

closest p · 1.2× alpha

0.0920

boldest claim

The sentences

showed a trendp = 0.0598so close (0.05 < p ≤ 0.1)

Although not statistically significant, an elevated cfDNA concentration in right-sided CRC also showed a trend toward poorer survival (504 vs 702.5 days; p = 0.0598; Fig. 3 B).

also in 53,322 other papers

a strong trendp = 0.092so close (0.05 < p ≤ 0.1)

did not reach statistical significancep = 0.092so close (0.05 < p ≤ 0.1)

Furthermore, although RAS mutation detection via a liquid biopsy did not reach statistical significance in the multivariate model, it showed a strong trend towards significance ( p = 0.092).

also in 5,725 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.