Ascites Bactericidal Capacity in Patients With Decompensated Cirrhosis.

Bacterial uptake 30 minutes postinfection (p.i.) did not significantly differ between strains, although there was a clear trend towards increased uptake of EC958Δ rfaH ( Figure 4 A ).

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The Δ waaL mutant showed a trend towards increased C1Q and IgG deposition, compared with WT EC958, but did not affect MAC assembly.

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We observed a significant trend towards decreased surface VSIG4 expression when ascites cells were incubated in AF compared with media or BPs ( Figure 5 E ), consistent with a previous report that VSIG4 can be rapidly shed from the cell surface in response to a variety of stimuli. 31 The decrease in VSIG4 surface expression, although lower in magnitude than the effect of AF incubation on BP uptake, increased the apparent percentage of VSIG4 Low cells, thereby influencing estimates of phagocytic capacity.

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