Co-regulation of HIV control and cytomegalovirus pp65-specific IL-1β and TNF-α responses by genetic variants in the MHC region.

PLoS Pathog · 2026 · PMC13367729 · PMID 42447072

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0.0520

closest p · 1.0× alpha

0.0520

boldest claim

The sentences

did not reach statistical significanceP = 0.052so close (0.05 < p ≤ 0.1)

This effect was also present in isolated CD8 T cells, although it did not reach statistical significance (P = 0.052; Fig 3b ).

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showed a trendno p-value reported

Of these cell types, only CD8 Tc17 and PD-L1 + neutrophils showed a trend of being lower in HICs versus non-HICs, although not statistically significant, in consistency with the genetic effects ( S9 Table ).

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nominally significantno p-value reported

Only nominally significant associations are shown and all effect sizes are given with respect to the alternative allele.

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