On this scale, we observed a clear trend to a lower synovial inflammation score in parp-1 o/o mice compared to parp-1 + mice (Figures 3 and 4 ), although the difference was not significant ( p = 0.058, by 1-way MANCOVA fixed effects test).
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Partial protection against collagen antibody-induced arthritis in PARP-1 deficient mice.
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The results also showed a trend to less damage in parp-1 o/o mice (Figures 3 and 5 ), although, again, the difference did not reach statistical significance ( p = 0.053, by 1-way MANCOVA fixed effects test).