Doxycycline reduces plasma VEGF-C/sVEGFR-3 and improves pathology in lymphatic filariasis.

PLoS Pathog · 2006 · PMC1564427 · PMID 17044733

Europe PMC DOI

hedged sentences

0.0514

closest p · 1.0× alpha

0.0514

boldest claim

The sentences

a strong trendp = 0.0514so close (0.05 < p ≤ 0.1)

No correlation was found between VEGF-C and lymphatic dilation, but a strong trend ( r = 0.390, p = 0.0514) was noticed between sVEGFR-3 and lymphatic vessel dilation.

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showed a trendno p-value reported

Lymphedema Stages Doxycycline treatment significantly reduced the stage of disease in lymphedema patients, whereas the stage was not significantly altered in placebo patients, who, rather, showed a trend towards deterioration.

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did not reach statistical significanceno p-value reported

USG results did show 20% loss of worm nests at 24 mo; however, this reduction did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.