Detection and significance of human papillomavirus, CDKN2A(p16) and CDKN1A(p21) expression in squamous cell carcinoma of the larynx.

Mod Pathol · 2013 · PMC3529982 · PMID 22996374

Europe PMC DOI

hedged sentences

0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

a strong trendp=0.058so close (0.05 < p ≤ 0.1)

There was also a strong trend towards better overall survival in the CDKN2A(p16) positive group (p=0.058).

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did not reach statistical significancep = 0.058so close (0.05 < p ≤ 0.1)

There was a trend towards better overall survival for p16 positive tumors as well but this did not reach statistical significance (p = 0.058, Figure 4 ).

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showed a trendno p-value reported

Furthermore, CDKN1A(p21) expression was associated with better overall patient survival (p=0.045), while CDKN2A(p16) expression showed a trend toward better overall survival, in univariate analysis.

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