Clinical outcome of HIV viraemic controllers and noncontrollers with normal CD4 counts is exclusively determined by antigen-specific CD8+ T-cell-mediated HIV suppression.

PLoS One · 2015 · PMC4357381 · PMID 25764310

Europe PMC DOI

hedged sentences

0.0003

closest p · 0.0× alpha

0.0003

boldest claim

The sentences

highly significantp = 0.0003actually significant

A highly significant correlation between in vitro HIV suppressive activity and pVL was observed (Spearman r = -0.7345, p = 0.0003).

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did not reach statistical significanceno p-value reported

Absolute HIVp24-specific CD8 + T cells with the full range of 5 functions were present in higher numbers in VC than NC (median 421 VS 169 cells/ml) but this did not reach statistical significance.

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failed to reach statistical significanceno p-value reported

Although VC showed a trend towards having greater absolute numbers of HIV p24-specific polyfunctional T cells, these findings failed to reach statistical significance.

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showed a trendno p-value reported

Similarly, the 4-function CD8 + T cells showed a trend towards higher levels in VC than in NC (3,365 VS 2,258 cells/ml, not significant).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.