Gene Expression Analyses during Spontaneous Reversal of Cardiomyopathy in Mice with Repressed Nuclear CUG-BP, Elav-Like Family (CELF) Activity in Heart Muscle.

In the severe line, all four SRF targets continued to show a trend towards increased expression compared to wild type at 24 weeks, but did not reach statistical significance (P = 0.15, 0.07, 0.10, and 0.07 for Tpm2 , Egr1 , Rcan1 , and Nppb , respectively).

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FHL1 levels in the severe line show a strong trend towards still being elevated at 24 weeks, although this difference is not statistically significant (P = 0.10), perhaps due to greater variability in the levels in the severe line.

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FHL2 levels also showed a trend towards increased levels at 24 weeks compared to 3 weeks, though this difference was not statistically significant.

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