reached borderline significancep = 0.088
Tumor size on day 16 reached borderline significance for values expressed as percentage ( p = 0.088, two-sided t -test) comparing the 0.5 mg/kg bw groups of both experiments with the saline controls.
Tumor size on day 16 reached borderline significance for values expressed as percentage ( p = 0.088, two-sided t -test) comparing the 0.5 mg/kg bw groups of both experiments with the saline controls.
Experiments with M21 melanoma xenografts (Figure 9B ) showed a trend for tumor growth retardation by tTF 218 -TAA either in the native or in a randomly TMS(PEG) 12 -PEGylated form.
However, this did not reach statistical significance, since experiments had to be stopped due to tumor size and animal regulation.