Analysis of Anthrax Immune Globulin Intravenous with Antimicrobial Treatment in Injection Drug Users, Scotland, 2009-2010.

For nonsurvivors, the time to death was longer for recipients than for nonrecipients in a pattern approaching significance (4.0 [3.0–5.0] vs. 1.3 [0.6–2.0]; p = 0.07) ( Figure 1 ; Table 6 ).

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However, in patients overall, risk for death at admission as reflected by the SOFA score was greater for AIG-IV recipients than for nonrecipients, although this finding did not reach statistical significance (median [IQR] 2 [0–7] vs. 0.5 [0–2.5]; p = 0.14).

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In these studies, AIG-IV added to the protective effects of antimicrobial drugs when both treatments were administered after the onset of lethality, in trends that approached significance ( 11 ).

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