Disease impact on the quality of life of children with inflammatory bowel disease.

Overall, total scores showed a significant trend across the PGA scale, with lower scores corresponding to worst clinical assessment (Mann-Whitney test, P < 0.001; Figure 1A ).

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Social functioning: A positive trend was recorded between age and social functioning scores, overall (Pearson's r = 0.21, P = 0.030), but not in stratified analyses.

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In general, patients with CD scored higher in all scales compared to ulcerative colitis group; however the results did not reach statistical significance, not even after adjusting for PGA level (all P values > 0.05).

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As shown in Tables 3 , 4 and 5 , across the study population, overall as well as in the sub-group analyses, there was a clear trend for bowel symptoms scores resulting in significantly lower scores for patients in the moderate/mild category compared to those classified in remission.

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