Deletion of TXNIP Mitigates High-Fat Diet-Impaired Angiogenesis and Prevents Inflammation in a Mouse Model of Critical Limb Ischemia.

Antioxidants (Basel) · 2017 · PMC5618075 · PMID 28661427

Europe PMC DOI

hedged sentences

0.0590

closest p · 1.2× alpha

0.0590

boldest claim

The sentences

did not reach statistical significancep = 0.059so close (0.05 < p ≤ 0.1)

As shown in Figure 5 A, HDF triggered an increase (1.8-fold) in circulating plasma IL-1β levels in WT-HFD group compared to WT-ND group; however, it did not reach statistical significance ( p = 0.059).

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showed a trendno p-value reported

Nitrotyrosine levels showed a trend of increase (1.4-fold) in their expression after ischemia alone in WT-ND mice.

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a strong trendno p-value reported

The basal level of CD68+ cells in the non-ischemic leg are shown in Supplementary Figure S2 where HFD exerted a strong trend to increase infiltration of CD68+ Cells compared to ND in WT mice, yet the increase did not reach statistical significance.

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