Epistatic Interaction of ERAP1 and HLA-B*51 in Iranian Patients with Behçet's Disease.

Sci Rep · 2018 · PMC6279803 · PMID 30514861

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failed to reach statistical significanceno p-value reported

The association also failed to reach statistical significance after Bonferroni correction.

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did not reach statistical significanceno p-value reported

This finding suggests an epistatic interaction between the rs30187 TT genotype and HLA-B*51 , but the association did not reach statistical significance after applying the Bonferroni correction. rs26653 was in moderate linkage disequilibrium (LD) with rs30187 ( r 2 = 0.37) (Fig. 1 ) and also showed a significant association in the recessive model of its risk C allele (Pro127Arg) in HLA-B*51 carriers (OR = 2.00) but not in the whole population.

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nominally significantno p-value reported

Three SNPs (rs1065407, rs10050860, and rs2287987) had a nominally significant association with BD in all subjects, and one SNP (rs26618) had a nominally significant association with HLA-B*51 positive subjects ( P < 0.05).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.