Association of Urinary Levels of Bisphenols A, F, and S with Endometriosis Risk: Preliminary Results of the EndEA Study.

In addition, TBARS concentrations showed a close-to-significant relationship with increased endometriosis risk [OR 1.6; 95%CI 1.0–2.8], and classification by TBARS concentration tertile revealed that the association between endometriosis risk and concentrations of BPA [OR 2.0; 95%CI 1.0–4.1] and Σbisphenols [OR 2.2; 95%CI 1.0–4.6] was only statistically significant for women in the highest TBARS tertile (>4.23 μM).

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When participants were classified by tertiles of BPA and Σbisphenol concentrations, a significantly increased risk was observed for the women in the second versus first tertile [OR 3.7; 95%CI 1.3–10.3 and OR 5.4; 95%CI 1.9–15.6, respectively] ( Figure 1 ), although a significant trend was not observed ( p -trend > 0.100).

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Σbisphenol concentrations were also associated with increased endometriosis risk (OR 1.5; 95%CI 0.9–2.3), but the association did not reach statistical significance ( p -value 0.089).

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