Mutually suppressive roles of KMT2A and KDM5C in behaviour, neuronal structure, and histone H3K4 methylation.

Commun Biol · 2020 · PMC7264178 · PMID 32483278

Europe PMC DOI

hedged sentences

0.0660

closest p · 1.3× alpha

0.0770

boldest claim

The sentences

did not reach statistical significancep = 0.066so close (0.05 < p ≤ 0.1)

In DM vCA1, spine density showed a trend of degrease compared to WT, yet this did not reach statistical significance (WT vs DM: p = 0.066).

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a strong trendp = 0.077so close (0.05 < p ≤ 0.1)

Similar to Kdm5c -KO, DM mice showed a strong trend towards less time with stranger mice compared to WT (WT vs DM: p = 0.077).

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showed a trendno p-value reported

Both Kmt2a -HET and Kdm5c -KO showed a trend of increased aggression and decreased submission when we combined frequency of all aggressive or submissive behavior types compared to WT (Fig. 3 c).

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