Survival benefit of radiation in high-risk, early-stage endometrioid carcinoma.

J Gynecol Oncol · 2020 · PMC7286749 · PMID 31912686

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0960

boldest claim

The sentences

approached significancep=0.060so close (0.05 < p ≤ 0.1)

Across all patients, comorbidity score was associated with increased CSM, non-white race approached significance (p=0.060), and lymph node dissection was not significant.

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approaching significancep=0.096so close (0.05 < p ≤ 0.1)

Compared to EBRT alone, receiving BT in addition to EBRT was associated with a survival benefit approaching significance in stage IB grade 3 patients (adjusted HR for CSM=0.59; 95% CI=0.32–1.10; p=0.096), but not in stage II grades 1–2 (p=0.932) or stage II grade 3 (p=0.366).

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did not reach statistical significanceno p-value reported

The addition of BT to EBRT was also associated with a trend toward improved cancer-specific mortality compared to EBRT alone, although this did not reach statistical significance, likely because the effect size is smaller in the setting of already receiving EBRT.

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