Association of CSF proteins with tau and amyloid β levels in asymptomatic 70-year-olds.

GAP43 instead showed a trend of higher levels in A+ individuals regardless of APOE ε4 carrier status, although the difference was not statistically significant (Fig. 3 d).

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Moreover, the group differences in association to p-tau did not reach statistical significance.

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Stratification based on CSF Aβ42/Aβ40 ratio and APOE ε4 carrier status did only display a significant trend in the levels of NEFM, with higher levels in the APOE ε4 carriers independently of CSF Aβ42/Aβ40 ratio.

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