Retinal Morpho-Functional Changes Following 0.19 mg Fluocinolone Acetonide Intravitreal Implant for Chronic Diabetic Macular Edema.

Adv Ther · 2021 · PMC8096132 · PMID 33948926

Europe PMC DOI

hedged sentences

0.0001

closest p · 0.0× alpha

0.0100

boldest claim

The sentences

highly significantp < 0.0001actually significant

A Wilcoxon test showed a highly significant decrease of CMT from baseline (473 ± 196 μm) to month 1–3 (371 ± 163) ( p < 0.0001).

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a significant trendp < 0.01actually significant

In follow-ups longer than month 3, in our study population, mean changes in BCVA, PhNR and b-wave amplitudes did not reach statistical significance, while CMT showed a significant trend toward decrease over time (Friedman’s non-parametric ANOVA, p < 0.01, n = 14).

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showed a trendno p-value reported

Nonetheless PhNR and b-wave amplitudes showed a trend toward improvement (as shown in Fig. 4 a, b).

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did not reach statistical significanceno p-value reported

These ERG positive changes tended to endure up to month 9–14, although they did not reach statistical significance after month 3.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.