Of note, no homotopic pairs of regions differed from one another in terms of modulation by linguistic demand or the interaction of domain by difficulty, though the anterior insula showed a trend toward an interaction, with less of a discrepancy between domains in the left anterior insula compared to the right ( p = 0.058).
(Note that the left pre-SMA/anterior-mid cingulate narrowly missed significance for modulation by linguistic demand, as seen in Figure 2 ).
The lack of main effects of domain was welcome, though less important, since only the contrast used to identify language regions could be impacted by main effects of domain; for that reason, we were not concerned that the main effect of domain approached significance for reaction time.
They found stronger intersubject correlations in language regions than MD regions, and focused their interpretation on this difference, but it is noteworthy that intersubject correlations throughout the MD network were still highly significant.
Three additional spheres were also defined around prominent right hemisphere peaks that did not reach statistical significance but were clearly homotopic to left hemisphere language areas: the pars triangularis of the IFG, posterior STS, and anterior STS.