Exploring Refinement Strategies for Single Housing of Male C57BL/6JRj Mice: Effect of Cage Divider on Stress-Related Behavior and Hypothalamic-Pituitary-Adrenal-Axis Activity.

Front Behav Neurosci · 2021 · PMC8581484 · PMID 34776890

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a clear trendno p-value reported

did not reach statistical significanceno p-value reported

In experiment 2, the suppression of plasma corticosterone following dexamethasone administration did not reach statistical significance in pair housed mice with or without cage divider but a clear trend was observed.

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showed a trendno p-value reported

Post hoc analysis, comparing the housing conditions, showed a trend but no significant difference in freezing between single housed and pair housed mice with a cage divider ( P = 0.0538) or between single housed- and pair housed mice ( P = 0.0560) during the fear retrieval test.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.