Monocytic-Myeloid Derived Suppressor Cells Suppress T-Cell Responses in Recovered SARS CoV2-Infected Individuals.

Front Immunol · 2022 · PMC9263272 · PMID 35812392

Europe PMC DOI

hedged sentences

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closest p · 1.4× alpha

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boldest claim

The sentences

approached significancep=0.07so close (0.05 < p ≤ 0.1)

Of note, the expression of STAT3 in M-MDSC of CoV2+ when compared to CoV2- participants approached significance (0.4 ± 0.3 vs 15.9 ± 10.6; p=0.07).

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showed a trendno p-value reported

In contrast, our transcriptomic data showed a trend of lower S100A9/A8 expression in CD14 + HLA DR lo M-MDSC isolated 5 months after the first detection of CoV2 ( Supplementary Table 2 ).

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did not reach statistical significanceno p-value reported

Many of these genes were previously implicated in severe CoV2 infection; including some genes that did not reach statistical significance in our study.

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