Barely Significant

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Control cancer cells displayed low E-cadherin levels, while both 5FU- and F6-treated cells showed a trend, albeit not significant, toward increased release ( Figure 8 a); β-catenin increases significantly only in 5FU+F6-treated cells, while showing a slight, albeit not significant decrease in the other treatment conditions ( Figure 8 b).
Looking at a possible correlation between methylation and clinic-pathological parameters, it was observed that the degree of promoter methylation showed a trend of association with a higher risk of progression, which is difficult to confirm due to the indolent course of disease of lung carcinoid and a large number of cases required for a validation in an independent cohort.
Plasma Exosomal miR-517-5p, miR-520a-5p and miR-525-5p are Down-Regulated during the First Trimester of Gestation in Women Affected with GH and PE The expression profile of miR-517-5p, miR-520a-5p, and miR-525-5p differed significantly or showed a trend toward statistical significance between the groups of women with later onset of GH or PE and the controls.