Barely Significant

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A 2 + 0.60 × B 2 − 0.12 × C 2 (1) It can be seen from Table 2 that the p -value (0.0389) for the breaking strength regression model was less than 0.05, indicating that the model was significant (a p -value less than 0.05 indicates a significant difference, and a p -value less than 0.01 indicates an extremely significant difference) [ 29 ].
Moreover, bleomycin treatment significantly decreased the levels of regulatory cytokine IL-10 (from 6.5 ± 2.3 to 1.7 ± 0.7 pg/mL), while MRS5980 administration showed a trend toward increased IL-10 levels in a dose-dependent manner (3.1 ± 1.0 and 4.7 ± 3.0 pg/mL, respectively), even if it was not statistically significant ( Figure 5 E).
This outcome was not observed in OS; however, significance was maintained when adjusting the result with the variables age and sex ( p -value: 0.044, HRa: 2.832, IC HRa: (1.029–7.794)), and it also remained very close to significance if the adjustment was performed by staging ( p -value 0.064, HRa: 2.597, IC HRa: (0.946–7.126)), as is shown in Figure 6 .