Excerpts

Specifically, the sampling period exerted a highly significant ( p < 0.001) main effect on the extracts, density, and refractive index ( Table 2 ).

For incurred eggs, ANOVA results were highly significant (F(6,28) = 76.65, p < 0.001).

Additionally, the ANOVA results of the model revealed that the effects of ethanol volume fraction, solid-to-liquid ratio, and extraction time on CE were highly significant ( p < 0.001).

The PCA (highly significant results p < 0.001, by permutational multivariate analysis of variance, PERMANOVA) showed that control plants grown under conditions of Fe sufficiency and those exposed to volatiles from L264 had similar mass spectra, since treatments were grouped together.

All the obtained values were statistically highly significant ( p < 0.001).

A p < 0.05 indicated significant (*), p < 0.01 indicated highly significant (**), and p < 0.001 indicated extremely highly significant (***) difference. 3.

Wound-healing was slowest in untreated group (A), showing the maximum diameter throughout the study period with wound closure 17.56% and 50.44% on day 5 and 10, respectively, while Group D, treated with commercial product, showed maximum healing of 49.1% and 95.3%, as shown in Figure 9 , which showed highly significant ( p < 0.001) results when compared to untreated groups, whereas Group C, treated with the CEO NFs, also showed better healing percentage (45.41 and 90.13) on the 5th and 10th day of treatment, which is more significantly different ( p < 0.01) from Group A, but less than that of the commercial product, as shown in Table 4 .

A highly significant difference in anti-VZV activity was observed between the purified flavonoid extract and the fresh juice group ( p < 0.001).

Compared with the blank group, arbutin group showed a highly significant tyrosinase activity of 75.056 ± 2.846 ( p < 0.001), the 400 μg/mL RGBs showed a tyrosinase activity of 84.545 ± 0.783, and the 400 μg/mL YGB showed a tyrosinase activity of 84.184 ± 2.240 ( p < 0.001), and it decreased with the increase in concentration. 2.6.

In this line, the contractile response to PE was tested and both compounds significantly reduced the contractile response to PE, although oxime–1 showed a more highly significant ( p < 0.001) reduction of the contractile response to different concentrations of PE (10 −7 to 10 −5 M).

The p -value of <0.05 was considered a significant difference, while p < 0.01 was considered as highly significant, and p < 0.001 was considered as extremely significant. 5.

The introduction of alloxan drastically increased the blood glucose level, which was highly significant ( p < 0.001) compared to the normal control group, and remained constant throughout the study period.

A one-way ANOVA test applied on the concentrations values of the identified compounds listed in Table 1 showed that there is a highly significant difference between these two extracts ( p < 0.001). 2.2.

For the responses of RSA, TIA, and CIA, the models were highly significant when the computed F-values were greater than the tabulated F-value and the probability values were low ( p < 0.001); this indicates that the individual terms in each response model were significant in terms of the interaction effect [ 37 ].

The type of solvent was highly significant ( p < 0.001) over all analyzed responses.

The coefficients of X 3 , X 1 X 2 , X 2 X 3 , X 1 2 , X 2 2 , and X 3 2 were highly significant ( p < 0.001), while those of X 1 and X 2 were statistically significant ( p < 0.01).

Statistical significance was defined as highly significant (*** p < 0.001).

A one-way ANOVA test applied on the concentrations values of the identified compounds listed in Table 1 showed that there is a highly significant difference between these three extracts ( p < 0.001). 2.2.

The potent anti-inflammatory drug dexamethasone (50 ng/mL), inhibited the LPS-induced nitric oxide production (5.2 μg/mL with LPS + dexamethasone compared to 25.2 μg/mL in the presence of LPS alone).The tested samples exhibited different extents of anti-inflammatory activity, ranging from strong to weak activity in the order 23 > 24 > 22 > 18 > 12 > 4 and their effect even greater than that of dexamethasone, with highly significant inhibition values ( p < 0.001) of 95.7, 95.4, 91.0, 90.9, 90.7, 90.4, and 90.1%, respectively, compared to the LPS induced cells ( Figure 2 ).

The ANOVA of the regression model demonstrates that the model is highly significant ( p < 0.001).

Although there was a weak trend (y = 0.23x − 142.1, p < 0.001) showing increased difference between the two methods ( Figure 7 c), this increase in difference is of small practical importance and in most cases the error will be smaller than the analytical precision.

There was a highly significant ( p < 0.001) enhancement of 2.7-fold and 3.6-fold in the permeation flux achieved in PLF3 and PLF3C1 than pure PPN, respectively.

The highest level was observed in the 40% combination group (CDDP 11.2 μM + ε-VNF 8.4 μM), reaching 4.3 ± 0.6 μM, which was found to be highly significant (*** p < 0.001).

The results of ANOVA analysis applied on peroxide values show highly significant ( p < 0.001) main effects (antioxidant and time) but also a highly significant ( p < 0.001) interaction effect.

Furthermore, the model’s structural stability was confirmed by CV-ANOVA diagnostics, which revealed a highly significant distribution ( p < 0.001), establishing the definitive validity of the chemometric classification.