Barely Significant

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highly significantp<0.00010.0× alphaqualifiedgold
As a cross-check, calculated (via DIC and TA) and directly measured pH values were compared and showed a highly significant correlation and no outliers (pH (total scale) = 0.9176 pH (NBS) +0.5453; r 2 = 0.99; p<0.0001).
highly significantp < 0.00010.0× alphaqualifiedgold
Age ranged between 2.0 and 5.2 years in the animals from the low-fluoride areas and between 1.6 and 13.3 years in those from the high-fluoride area ( Table 2 ) The difference in bone fluoride concentration between the two groups was highly significant (p < 0.0001), whereas no significant difference existed for age (p = 0.12) ( Table 2 ).
highly significantp = 0.00010.0× alphaqualifiedgold
The effects of the study drugs on gut microbiome β-diversity at the OTU level were first tested statistically using a two-way NPMANOVA and the results revealed highly significant main effects for drug (F 4,65 = 3.35; p = 0.0001) and time (F 2,65 = 8.43, p = 0.0001), as well as a significant interaction (F 8,65 = 1.77, p = 0.0001).
highly significantP<0.00010.0× alphaqualifiedgold
When all observations of Xe effects on freezing at PR-LTM1 were pooled from these two independent experiments (Air-exposure, n = 20; Xe-exposure, n = 21) there was a highly significant reduction in freezing both to context alone ( t 39 = 4.63, P<0.0001) and context + tone ( t 39 = 2.16, P<0.01) compared to air-exposed controls.
highly significantp<0.00010.0× alphaqualifiedgold
The number of scales did not show significant differences among the four southern phenotypes (diagonal, vertical and longitudinal bars, and stellate spot; GLM: all p>0.4), whereas the difference was highly significant between these four phenotypes and the round spot skin pattern (GLM: t = 11.9, p<0.0001).
highly significantP <0.00010.0× alphaqualifiedgold
The results presented in Figure 1B–C clearly support our hypothesis: antibody treatment did not significantly impact tumor growth in B16.F10 challenged mice ( P = 0.1850); whereas the effect on B16.F10-GP challenged mice were highly significant ( P <0.0001).
highly significantp<0.00010.0× alphaqualifiedgold
Spearman's rank correlation for race frequency between the three collection efforts was highly significant for all cases (p<0.0001; Rho for 1950*1975 = 0.72, 1950*2005 = 0.63, and 1975*2005 = 0.73) and also between each of these efforts and the whole sample (p<0.0001; Rho 0.77, 0.86, and 0.95, respectively for 1950, 1975 and 2005).