Barely Significant

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highly significantqualifiedgold
In contrast to our previous study, however, survivors and non-survivors in this study showed significant or even highly significant differences in pulmonary gas exchange and ventilator therapy (e.g. mean and minimum values for oxygen saturation and partial pressure of oxygen, mean values for the fraction of inspired oxygen, positive expiratory pressure, tidal volume, and oxygenation ratio).
This borderline significant difference was still evident at 12 months of age (maternal iron supplementation 7.6 ± 0.8 mm (n = 11), no maternal iron supplementation 7.1 ± 0.6 mm (n = 37), adjusted p = 0.04) but had disappeared by 24 months of age (maternal iron supplementation 6.6 ± 0.6 mm (n = 9), no maternal iron supplementation 6.5 ± 0.5 mm (n = 32), adjusted p = 0.5).
In regard to the efficacy of sequential treatment with TFTD and regorafenib administered in the forward or reverse sequence, it is generally considered that there are no differences in the conventional parameters of efficacy, whichever of the two agents is used first [ 9 – 12 ], while some reports showed that patients who received TFTD after regorafenib treatment showed a trend towards a longer PFS than those who received it prior to regorafenib [ 24 ].
highly significantqualifiedgold
Our finding however of a highly significant difference in the carriage rate of F . nucleatum DNA in CRC patient stool samples when compared to stool samples from healthy controls confirms other reports that suggest these bacteria are well represented in the lumen of the gut [ 12 , 15 , 19 ], in addition to being present in tissue samples as shown here and by others [ 11 , 12 , 15 , 23 ].