Excerpts

All six models listed include cannabinoids with highly significant positive terms (from β-est. = 3.67 (2.77, 4.56), P = 3.06 × 10 –12 ) in model four) and in all six models the effect of cannabinoids is positive overall.

STRING protein interaction analysis yielded a highly significant protein-protein interaction (PPI) score (PPI score p = 8.26e- 12 ), suggesting these proteins might directly interact or work together in common pathways (Fig. 1 D).

The correlation between our CNV prediction and PCR validation was highly significant (P = 8.92E-12) (Additional file: Figure S2 ).

The overall differences between the incidences of the tested neuronal markers among the virus delivered eGFP expressing neurons were highly significant, the Kruskal Wallis H test between groups: Hdf = 61.2, p < 1e − 11.

In Mp toc1 ko mutants, expression of Mp PRR was continuously high and arrhythmic, as indicated by highly significant effects of both genotype (G) and genotype x time interaction (GxT) terms in ANOVA ( P < 10 −11 ), suggesting that MpTOC1 represses Mp PRR .

The resulting ICC(A,1) was 0.99 (95% CI: 0.0967-0.997), and the F-test confirmed that this level of agreement was highly significant (F(15, 10.6)=250, p=2.42x10 -11 ).

The accuracy T-test shows a highly significant difference (t = 14.84, p = 3.65e-11) in accuracy between M-Net and SOTA CNNs.

The two-way ANOVA (response: OD at 517 nm; factors: Treatment and Experiment) indicates a highly significant main effect of Treatment (F 2 ,12 = 319.43, p = 3.93 × 10−11), demonstrating that absorbance differs markedly among the control, thyme oil, and cinnamon oil groups.

One-way ANOVA revealed a highly significant effect of the dose group (F = 183.3, p ≈ 6.7 × 10− 11 ).

The regression model was highly significant (F = 33,119.09, p = 9.51 × 10− 11 ), with slope of 1.0150 (95% CI 1.0007–1.0293) and intercept of 1.0626 (95% CI 1.0327–1.0924), confirming statistical significance of both parameters.

In this regard, the change in CD66b expression by bound cells was highly significant, p < 10 –10 and P < 10 –5 compared to BSL and CIRC respectively (Fig. 3 c).

For each of the module, we have assigned the clinical annotation, when it is highly significant (p < 10 −10 ) and when the minimum hit of the module genes on cancer pathways is atleast 50%.

Hypergeometric enrichment analyses showed that these overlaps were highly significant ( p < 1e−10), supporting a non-random and biologically meaningful association among these factors (Fig. 3 C).

Nevertheless, a highly significant, positive correlation, was found between the qPCR and RNA-seq analyses (r = 0.91, P = 1.07 × 10 −10 ; Fig. 5e ), which supported an overall concordance between the results of the two techniques despite the low replicate number for RNA-seq analysis.

The main effect for the participant group was highly significant (F(1, 332.00) = 44.29 and P = 1.17 × 10 −10 ).

Recently, a genome-wide association scan with a subsequent replication study involving over 67,000 individuals (7,473 cases and 42,938 controls) of European ancestry produced highly significant evidence of the strong association of a single nucleotide polymorphism (SNP) rs11177 (C/T) with severe hip and knee OA ( P value = 1.25 × 10 −10 ), a missense polymorphism within the nucleostemin-encoding gene GNL3 19 .

Interestingly, we found a highly significant overlap between differentially expressed and alternatively transcribed genes in LPS response (63/150, hypergeometric test p < 2.4 × 10 −10 ), but no significant overlap between differentially expressed and alternatively transcribed genes between MDMs and IPSDMs (28/140, hypergeometric test p < 0.74).

This enrichment is highly significant (hypergeometric test followed by Benjamini–Hochberg FDR correction 33 : expected 7.5 TK, observed 24 TK, p = 3.2 × 10 -10 , FDR-corrected q = 1.9 × 10 -9 ).

6 d), with the TG association remaining highly significant even after adjustment for these metabolites (p = 4.4E−10).

gondii dataset showed highly significant improvements over ResNetKhib ( p = 6.11 × 10−10), DeepKhib ( p < 10−16), iLys-Khib ( p < 10−16), and KhibPred ( p < 10−16).

The changes in frequencies of each of these were highly significant (P < 10 −9 for each, remaining significant after Bonferroni correction for scanning all nucleotide positions in the genome; Table S2 ).

We found a highly significant non-random association of non-silent TP53 mutation to HPV negativity (Fisher’s exact test Odds Ratio = 0.14, p < 10 −9 ), suggesting an underlying association, and this was not included in the multivariate analysis.

The latency of this response was faster for faces presented in the proximal than in distant condition (1467 ± 66 and 1690 ± 59 ms respectively) and this difference was highly significant (F = 52.0, p < 10 –9 , Fig. 2 C).

Among all the modules, the turquoise module showed a highly significant association with fibrosis and inflammation levels ( P = 1 × 10 −09 for fibrosis stages and P = 1 × 10 −10 for inflammation grades).

3 c pattern, the separations between data-point distributions for all nearest-neighbor pairs of pre -transition States are highly significant in one or both of the ΔHbO 2 Sat ( p = 1.2 × 10 −9 –9.3 × 10 −4 ) or ΔtotalHb ( p = 5.5 × 10 −5 –4.3 × 10 −4 ) dimensions.