Significant differences were also observed across multiple subscales, with a highly significant difference in sleep duration between the JIA group and the control group ( p = 0.000), as well as significant differences in sleep anxiety ( p = 0.046), night awakenings ( p = 0.002), abnormal sleep patterns ( p = 0.003), sleep breathing disorders ( p = 0.000), and daytime sleepiness ( p = 0.007).
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Medication (analgesics, triptans, ergotamine) was used by 98.7 % of the patients at baseline and by 89.9 % of patients at the 1-year follow-up with a highly significant reduction in the number of days with medication use per month (pre: M = 10.92 ± 7.31; follow-up: 3.99 ± 3.62; ( t = 9.686, df = 157, p < 0.000).
The mean value of number of oral neutrophils was found to be highly significant (p = 0.000) among healthy and severe periodontitis, gingivitis and severe periodontitis, mild periodontitis and severe periodontitis, and moderate periodontitis and severe periodontitis [ Table 5 and Graph 2 ].
Highly significant results were those with a significance level of p < 0.000.
As it is shown in Table 2 , there was a statistically highly significant difference among the 3 groups concerning overall lesions as determined by one-way ANOVA ( P = 0.000).
The highly significant effect is of actual behavior on academic performance as (β = 0.558, t value = 9.571, p values = 0.000, p < .01).
After adjustment to these covariants, the number of potentially harmful MEs decreased highly significant after the introduction of the electronic prescribing system ( p = .000).
While the increase in cotton level between lint filter and condenser stages is not statistically significant, the high proportion of cotton fibers observed in the condenser water is highly significant versus lint filter and condenser stages (t-test p = 0.00 for both).
A highly significant difference was observed between BAG and Nano-HAP groups (mean difference = −8.731, p = 0.000), with the Nano-HAP group showing superior hardness values ( Table (3) , Table (4) , Figure (7) , Figure (8) ). 3.3 Correlation between phosphate and VHN Pearson correlation analysis across all groups revealed a statistically significant positive correlation between phosphate Raman peak intensity and Vickers microhardness values (r = 0.600, p = 0.000), suggesting that increased mineral content is generally associated with higher surface hardness.
Visually the distributions are quite distinct, with TE derived exons having far lower coding potential, and accordingly there is a highly significant difference between the two coding probability distributions, D = 0.67 P = 0 Kolmogorov-Smirnov test (Figure 4A ).
There was a highly significant association between the source of information and the level of knowledge about the causes of ASD (P=0.000).
RESULTS: During the study period, there were 2,646,194 deaths from IDCs among the elderly, with a decreasing trend (ß -0.545; confidence interval, CI: -0.616 to -0.475; P < 0.000) for both males and females.
Our logistic regression model was significantly better as it explained more of the variance in the outcome, which was reflected by the highly significant chi-square value (chi-square = 2365.3, df = 17, p < .000).
A highly significant reduction ( p < 0.000 ) of TDS was observed in the effluent compared to influent samples. pH is defined as measure of hydrogen ion concentration. pH of the untreated sample was greater than 7 and were up to the maximum value of 10 as shown in Table 1 .
It is worth noting that the difference with the control group was highly significant with combo ( p = 0.000) (Fig. 2 C, Supplementary Table S3 ).
A highly significant difference was reported between the two GMs (p = 0.000).
Among the HCC patients, 22/30 (73.3%) had mean sTNFR-II levels of ≥ 398 pg/ml, whereas only 2/17 (11.8%) cases with PNALT had this value with a highly significant difference ( p = 0.000).
A highly significant difference was observed between groups (P = 0.000) and between garlic and the other materials (P = 0.000).
All the correlations are observed to be highly significant (p = 0.000).
However the pooled regression model exhibits potential biases by failing to consider hierarchical effects, evidenced by elevated coefficients for variables. In Table 7 , the ML model exhibits a robust model fit, evidenced by a highly significant Wald chi-square statistic (1439.560, p < 0.000) and a low residual variance (0.023 with a standard error of 0.001), signifying that the model significantly accounts for variability in the data.
When stratified by disease stage, individuals diagnosed at Stage I–III ( n = 142) exhibited significantly more favorable survival trends than those with Stage IV tumors ( n = 36), with highly significant survival differences ( p < 0.0000; Figure S3 ).
4 b) also supports this finding with a highly significant enrichment score (NES = 2.62, p = 0) and a clear bias towards the upregulation of ribosomal genes in the AD group.
In the GDP model, this variable has a strong positive and highly significant coefficient ( β = 0.447, p = 0.000), indicating that greater participation in online courses among people aged 55–74is associated with higher GDP per capita.
Regarding cardiac function, irrespective of PPI, a decreasing trend in LVEDD (PM: –4.19 mm, NPM: –6.16 mm, p = 0.000) and an increasing trend in LVEF (PM: +2.19%, NPM: +2.74%, p = 0.053) were observed.
Associations between GSTP1 percent methylation and child spirometry In the sample as a whole, high percent methylation was associated with decreases in FEV 1 (z-score = − 0.38, p = 0.06) and FEF 25–75 (z-score = − 0.38, p = 0.05), adjusting for maternal age and education (Table 3 , Model 1) although associations did not quite reach statistical significance at the p < 0..05 level.