Barely Significant

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highly significantP ≤ 0.0010.0× alphaqualifiedgold
(The percentiles being compared are reversed because greater Aβ is associated with greater risk, while smaller hippocampal volume is associated with greater risk.) Both Aβ load and MRI were highly significant predictors of progression overall ( P ≤ 0.001 for both) ( Table 2 ).
an overall trendP < 0.0010.0× alphagold
As expected from earlier SAR work on this series, 6 , 7 , 8 there was a good overall correlation between the MABA and LORA MIC 90 values for the compounds: (1) l o g MABA = 0.98 ∗ l o g LORA - 0.08 n = 58 , R = 0.85 , p < 0.001 , F 2 , 56 = 144 Also, as expected, there was a reasonable correlation between inhibitory activity (illustrated here for MABA data) and compound lipophilicity, with the more lipophilic compounds being more potent; an overall trend repeatedly seen in other classes of TB drugs. 12 , 13 (2) logMABA = - 0.50 ∗ c l o g P + 1.97 n = 58 , R = 0.71 , P < 0.001 , F 2 , 56 = 55 However, this overall correlation masks a trend seen to some extent previously, 8 that for this general class of compound, MIC 90 potency falls off quite sharply for compounds (e.g., 3 , 8 , 16 , 18 , 23 , 25 , 27 , 29 , 31 , 42 , 44 , 52 ) of lower lipophilicity (clogP values around 4 or below).
highly significantp<0.0010.0× alphaqualifiedgold
A highly significant correlation was finally observed in the entire study population between RBC count and hematocrit (r=0.74; 95% CI, 0.68 to 0.80; p<0.001), hemoglobin (r=0.81; 95% CI, 0.76 to 0.85; p<0.001), MCV (r=-0.51; 95% CI, -0.60 to -0.40; p<0.001), MCH (r=-0.48; 95% CI, -0.58 to -0.37; p<0.001), sTFR (r=0.16; 95% CI, 0.03 to 0.29; p=0.020) and transferrin (r=0.16; 95% CI, 0.03 to 0.29; p=0.015), but not between RBC count and MCHC (r=0.10; 95% CI, -0.03 to 0.23; p=0.138) or ferritin (r=-0.13; 95% CI, -0.26 to 0.01; p=0.056).
highly significantp < 0.0010.0× alphaqualifiedgold
As expected, paired t -tests for the valence ratings showed highly significant differences between negative and positive stimuli, for both faces and words (Faces: t (34) = −20.18, p < 0.001; Words: t (34) = −34.25, p < 0.001), thus validating the employed category grouping of the experimental stimuli.
highly significantP < 0.0010.0× alphaqualifiedgold
We found that the paired subsamples had highly significant positive correlations in VAF (%), as shown for #M42 (R 2 = 36.7, P < 0.001; Fig 2B ), which we present because it was the most widespread de novo floral mutation in Flower #2 and present in all 20 split samples and with the combined data for all 37 de novo mutations of Flower #2 together (R 2 = 79.5, P < 0.0001; Fig 2C ).
highly significantp < 0.0010.0× alphaqualifiedgold
4.10 Clinical outcome As a result, in the patients' group, endothelial function improved as expressed by the highly significant increase in CFR during the RR session (p < 0.001) and after 60 days (p < 0.05) and a reduction (p < 0.05) of IMT in the carotid vessels after six months ( Fig. 7 ).