Barely Significant

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highly significantP < 0.0010.0× alphaqualifiedgold
A Friedman’s analysis of variance (ANOVA) with Bonferroni correction of the difference suppression values at different test frequencies in the total participants group indicated a statistically less suppression for 4000 Hz compared to 2828 Hz ( P < 0.03) and highly significant difference between the following frequencies: 4000 and 2000 Hz ( P < 0.001); 4000 and 1001 Hz ( P < 0.001); 4000 and 1414 Hz ( P < 0.001); 2828 and 2000 Hz ( P < 0.001); 2828 and 1001 Hz ( P < 0.001) and 2000 and 1001 Hz ( P < 0.001).
highly significantp < 0.0010.0× alphaqualifiedgold
Quantification of the staining intensity demonstrated a highly significant ( p < 0.001, Wilcoxon rank test) increase in protein expression for Calnexin (1.6-fold) and AnxA2 (1.5-fold) and a 1.3-fold increase of AnxA5 (at the border of significance, p = 0.05) ( Fig. 6 ).