Strikingly, all 41 IFN-responsive target genes are induced to a higher level in the keratinocytes harbouring higher Wnt5a levels, corresponding to a statistically highly significant 1.8±1.1-fold relative hyper-induction across all target genes (p = 0.001).
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Evaluation of antioxidant activity of trans-crocetin in vitro The scavenging ability of trans-crocetin for superoxide anion (•O 2 − ) was evaluated by the lumino-DMSO-NaOH luminescence system, and as shown in Table 5 , trans-crocetin had more vital scavenging abilities than the positive control ascorbic acid, with highly significant differences ( P < 0.001) compared with the control group.
Differences were all highly significant between all pairs of subsets ( P <0.001).
Correlation between Soil Fungal Communities and Soil Properties in Grasslands of Mining Regions Exhibiting Varying Levels of Restoration The correlation analysis between soil fungi and soil physicochemical factors in the grasslands across various restoration stages levels in the Qianmalong mining area indicates, at the phylum level, a significant negative correlation between unclassified_k_Fungi and SOC and NO 3 -N ( p < 0.05), while Olpidiomycota demonstrated a highly significant positive relationship with SOC ( p < 0.001) and a significant positive correlation with TN and NO 3 -N ( p < 0.05) ( Figure 14 a).
The Bartlett's Test of Sphericity was highly significant (χ 2 = 167.5, p < 0.001), supporting the suitability of the data for factor analysis [ 29 ].
The number and activity of platelets adhered to the CC-SiNf substrate was lower and highly significant than that on flat Co-Cr surface (*** p < 0.001) ( Figure 7 II(c,d)).
These measurements revealed a highly significant difference in ET among regions (Kruskal–Wallis test, χ2 = 76.273, df = 4, p < 0.001, n = 100 measurements from five sites; Fig. 3 A).
All breed effects were found to be highly significant ( p < 0.001), with the exception of the effects on the claws ( p = 0.054), the heels ( p = 0.023) and the scrotum ( p = 0.009).
There is a highly significant (p < 0.001) time-dependent difference in age distribution.
ROC curve had a highly significant area under curve (AUC) (0.964, P<0.001).
There were highly significant differences in the major amputation rates of the two groups (revascularized and not revacularized), both in the early period (χ 2 = 162.6054, P < 0.001) and during follow-up (χ 2 = 64.3614, P < 0.001).
Furthermore, all pairwise group comparisons in the post hoc tests suggested highly significant group differences ( p < .001).
When entered, the resulting model was highly significant ( r 2 = 0.29, F 1,39 = 16.13, p <0.001) and SIPS disorganization was a significant predictor ( β = −0.54, t = −4.02, p <0.001; see Figure 2 ), indicating that a higher score on disorganization symptoms at baseline was predictive of a poorer functional outcome.
Model IV (versus model III), shows that the influence of A is highly significant since removing it from the model results in a considerable worsening of fit (χ 2 (1) = 293.2, p <.001).
Post-hoc contrasts comparing QoM averages between conditions revealed a highly significant effect ( t(69.8 )=4.86, p <0.001; see top left panel of Figure 5 for QoM averaged across PMs).
Age was a strong determinant of CVD risk: 46.2% of CVD cases occurred in individuals older than 60 years, whereas only 13.0% were younger than 40, with highly significant differences across age strata ( p < 0.001).
All raw data were analyzed through 3 repeated tests, and the results were presented as means ± SD, in which significant differences ( p < 0.05) and extremely significant differences ( p < 0.001) were analyzed.
Sperm Motility The sperm motility was scored and it was observed that there was highly significant ( P < 0.001) decrease in the percent sperm motility in Phase I after samples were exposed to Phenol-hydroquinone as compared to normal control samples.
Gene-specific differences reaching statistical significance ( P -values <0.05 for 39 genes, see Supplementary Table 1 ) were validated in a rescreen, enabling selection of 25 hits with highly significant differences ( P -values <0.001, Figure 1c and Table 1 ).
However, pain × fever, pain × fever × sleep, and pain × fever × fatigue/weakness, significant at P <0.05 or P <0.01 in separate three-way (second-order) explanatory models (regressions 2 and 3), all become highly significant ( P <0.001) in this simultaneous model (regression 4).
The −0.064 difference in the mean polarization was statistically highly significant ( t = −4.008, P < 0.001) with 31 degrees of freedom.
Moderately significant agreement (slope = 0.50, R 2 = 0.28, p < 0.001) was observed between epidemic duration estimates derived by the MCM and ETM.
There was a highly significant difference in fGCM concentrations between sites (Kruskal-Wallis test, chi-squared = 15.499, df = 2, p < 0.001), with multiple comparisons showing values from Wildendürnbach to be significantly lower than those at Czech sites, which showed no significant difference.
In the full dataset model, intraoperative CT (ioCT) emerged as a highly significant predictor, increasing skin-to-skin time by an estimated 38.1 min (p < 0.001) after adjustment for surgeon volume, screw and cage counts, decompressed segments, and other surgical factors.
Although the LMR was non-significant ( p = 0.1338), we relied on the highly significant BLRT ( p < 0.001), which is widely regarded as a superior metric to LMR-LRT for detecting the correct number of classes ( 12 ).