Barely Significant

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showed a trendp = 0.00100.0× alpha
Notably, we confirmed significantly decreased NE levels in the spinal cord of SMNΔ7 mice at P6 and showed a trend towards reduction of this neurotransmitter levels at P3, compared to the age-matched WT littermates (genotype, F (1,49) = 12.31, p = 0.0010; age×genotype, F (2,49) = 2.923, p = 0.0632; P3, p = 0.0938; P6, p = 0.0003; Fig. 4g ; Supplementary Table 4 ).
highly significantP <.0010.0× alphaqualifiedgold
To examine the children in the proximity of cutoff thresholds, we also used the 80th percentile cutoff point (ie, abnormal or border range), which showed that 36 (97%) children were above the cutoff point at baseline, while the respective figure at the 24-month follow-up was 23 (62%), indicating a highly significant change ( P <.001, McNemar test).
highly significantP < 0.0010.0× alphaqualifiedgold
The K values decreased further in the postoperative period and the change was highly significant ( P < 0.001) as compared to preoperative value but not significant ( P = 0.059) when compared to intraoperative values. α-angle (which represents the speed of solid clot formation) measured at preoperative, intraoperative, and postoperative time points had mean values of 54.80 ± 5.40 min, 61.94 ± 7.87 min, and 68.57 ± 5.70 min, respectively [ Table 3 ].