Excerpts

Furthermore, for oral squamous cell carcinoma patients, statistically, the difference was very highly significant ( P < 0.001).

Highly significant differences in VK2 serum concentrations between controls and MS patients were found ( p < 0.001) with controls showing more than three-fold higher levels on average.

The mean (± SEM) cAL increase was 11 ± 2 μm at 3 D, 14 ± 2 μm at 6 D, and 26 ± 2 μm at 9 D, with all pairwise comparisons highly significant (all P < 0.001), except the difference between the 3 and 6 D stimuli ( P = 0.48).

Results: Statistically highly significant relief ( P < 0.001) was noted in Amlodgara , Hritkantha Daha , Utklesha and Agnimandya and statistically highly significant relief ( P < 0.01) was seen in Gaurava and Avipaka .

The analysis yielded highly significant positive associations for the following variables (listing according to strength of association): previous ablation therapy ( p -value < 0.001; OR 3.87), previous family history of CAD ( p -value 0.011, OR 2.57), previous electric cardioversion ( p -value < 0.001, OR 2.54), substitution therapy with magnesium ( p -value < 0.001, OR 2.32), administration of beta-blockers ( p -value < 0.001, OR 1.91).

The resistance rate of cefepime decreased from 9.4% to 4.8%, showing a decreasing trend year by year ( p < 0.001).

Heterozygous (AC) carriers of the A1298C variant demonstrated highly significant protection against CRC development (RR = 0.2, p = 0.001), while a two-fold higher risk for CRC was estimated for homozygous genotype (CC) carriers.

There was a highly significant correlation between CTX and P1NP for all groups (all P < .001) for both fasting concentrations (R 2 = 0.64, 0.73, and 0.53 for the UK, The Gambia, and China, respectively) and the 24-hour mean (R 2 = 0.71, 0.75, and 0.58 for the UK, The Gambia, and China, respectively).

EPI-PNPs demonstrated significantly high oral bioavailability (AUC 0–∞ , significantly high P < 0.05) when compared with plain DOX-NPs, reported in previous work [ 53 ], EPI-MNPs also showed higher oral bioavailability however difference was extremely significant (P < 0.001).

However, the most striking contrast is observed in thrombophilia, where difference deliver a highly significant p -value of <0.001.

In this late phase, mesdopetam (3 and 10 mg/kg) and amantadine showed a highly significant antidyskinetic effect compared to vehicle treatment (Figure 2B right panel; p < 0.001; GLME and Tukey‐HSD test; it should be noted that in the current design, amantadine was injected 30 min earlier than mesdopetam, possibly explaining the temporal difference observed).

The differences in seropositive rates were statistically non-significant with clade S/wild type (Wilcoxon Signed Ranks test; p = 0.3170), but highly significant with the Delta variant (Wilcoxon Signed Ranks test; p = 0.001) ( Table 2 ).

Enterocloster had the strongest association with the lean group (mean difference −2.74, effect size −0.63), with highly significant results (Wilcoxon p < 0.001, FDR-adjusted p < 0.001; Welch p < 0.001, FDR-adjusted p = 0.013) ( Figure 5 , Table 6 ).

Data are expressed as means ± standard mean error and differences were considered as significant (∗p < 0.05), very significant (∗∗p < 0.01), or highly significant (∗∗∗p < 0.001).

A Kruskal-Wallis test indicated a highly significant difference (chi-square = 25.783, df = 3, P < 0.001) between δ 13 C en of humans from Aratu and Una traditions, Caatinga rock shelters, and rock shelters with unclear cultural context (table S15).

Importantly, a highly significant Group × Item Type interaction ( F (1, 1795) = 23.43, p < 0.001) was observed.

Results Very highly significant differences were found for time required to perform the exercise (increase of 76%, t(68) = 7.22, P < 0.001) and for accuracy (decrease of 6%, t(68) = − 3.69, P < 0.001) between patients and healthy subjects.

shasta and the absence of contemporary spawning by chum salmon was highly significant (χ 2 = 10.73, df = 1, p = 0.001; Table 5 ).

The linear mixed model yielded a highly significant coefficient of 5.7 for difference in modality ( P < 0.001), supporting the mean difference from the Bland-Altman plot.

The TG genotype in patients shows a highly significant difference from controls (odds ratio [OR], 2.104; [CI], 95% (1.406-3.147); P < 0.001), increasing the risk of NSCLC in comparison with the TT genotype (wild type).

The prevalence of MetS in cases (53%) was statistically very highly significant when compared to the controls (17%) ( P < 0.001).

The mean difference between results did not follow a normal distribution and we therefore tested the median difference using the non-parametric one-sample Wilcoxon Signed Rank test (step 3), showing a highly significant (p < 0.001) difference of 824 kg CO 2 -eq.

6 B , red line) was highly significant for both CAMs and OE21 cells (Fisher exact text, p < 0.001 in both cases).

This difference was highly significant (χ 2 (1) = 13.605, p < 0.001), with a moderate-to-strong association between technique and outcome (Φ = 0.415, Cramer’s V = 0.415, p < 0.001).

Pairwise F ST values among the four groups ranged from 0.130 to 0.341 and were all highly significant ( p < .001, Table 1 ).