All bleaching groups exhibited a highly significant and greater whitening difference compared to the control group (data not shown; p < 0.00000001, as determined by Dunnett's post hoc test).
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A highly significant association was observed between haplogroup and both language class (Cramer's V = 0.20, p<10 −8 , Table 1 ) and language group (V = 0.41, p<10 −8 , Table S3 ).
Pearson correlation coefficient between replicate transfections was highly significant, reaching 0.88 ( P < 10 −8 ); however, the overall correlation between exogenous and endogenous NSE levels was only 0.35 ( P < 0.01).
In new Figure 3D , the cluster area plot shows a visible and statistically significant difference in ZitP cluster area between the swarmer and stalked poles as supported by the highly significant difference observed (p < 10 -8 ).
These genes were either associated with resistance to both lead and cadmium in both sexes or had highly significant ( P < 10 −8 ) effects in any one condition.
There was no significant difference in the family effect between years (interaction family × year not significant; LRT: χ 2 = 1.2; df = 2; p = .552), but the family effect was highly significant ( χ 2 = 32.6; df = 1; p = 1 × 10 ‐ 8 , Table S2 ) and the heritability of the sensitivity to vernalization was 0.19 (±0.04) (Table 2 ).
Statistical analysis showed that the increase in inter-click angle was highly significant ( Figure 2A , bottom: one-way ANOVA: F >71, p <10 −8 ; post-hoc t tests: p <10 −11 for comparing one-object experiments after locking versus no-object experiments; p <10 −6 for multiple-object experiments after locking versus one-object after locking).
Most regions demonstrated significant heritability contributions to KC, particularly chr8:79,756,170–81,340,231, which exhibited highly significant h2 across KC, AD, AC, and AA (all P < 1 × 10−8).
All of the heritability and correlation estimates were highly significant ( p < 1 × 10 −8 ).
All of these regions showed highly significant associations (− log 10 P value > 8**) at the developmental stages after AP (i.e.
Effects of the virus inoculated, the dpi, and the interaction virus-dpi were highly significant on virus accumulation variations (p < 10 -8 , Fisher-Snedecor's test).
Compared to peaks containing L-CTCF-BSs, P-CTCF-BSs exhibited a higher mutation rate of 1.34 and 1.25 times per CTCF-BS for LNCaP and MCF7 respectively ( Supplementary Table S4 ), and the elevated rate is highly significant ( P -value < 1 × 10 −8 ) as determined by a permutation test (Materials and methods) (Figure 2A , B ).
PCs one, two, four, and five were all highly significant in association tests with cases and controls (all p ≤ 10 -8 ).
The effect size of the differences observed is very large, and the P -values highly significant ( P < 10 −8 ).
The observation that 20 AE-linked cytobands were found in the top 70 hits is highly significant ( P <10 −8 , hypergeometric distribution, with 624 total cytobands in the genome), whereas only 2 cytobands are expected to overlap by chance alone.
The univariate ANCOVA model applied (equation 2 ) revealed very highly significant differences between (1) the culinary oils investigated ( p < 10 −8 , with the exception of cis -2-alkenals for which p = 4.85 × 10 −3 ), and (2) sampling time-points ( p < 10 −8 ) for all aldehydes monitored.
All of these predictors gave highly significant ( P < 10 -8 ) improvements over random pairs.
All enrichments for GO ontologies representing these six biological processes were highly significant; P <10 −8 .
The results show also a highly significant p value for vessel diameter in the DCP in SWS patients compared to controls ( p = 0.00000001) ( Table 2 ).
Paired statistical tests across all datasets indicate that these improvements are highly significant ( p < 1 × 10 −8 ).
This enrichment is highly significant ( p = 1 × 10 −8 ), especially when considering that all miRNAs may not necessarily disrupt transcript levels.
While we found no obvious and consistent correlations between GWAS gene significance and FCs (electronic supplementary material, figure S4 a–g ), we identified GRIN2A and KCNB1 with highly significant GWAS associations ( p < 10 −8 ) in all seven diseases, and more strongly upregulated TL (FDR < 0.05, log 2 FC (TL/FL) > 1) in either both INH/EX ( GRIN2A ) or in INH ( KCNB1 ) ( figure 1 f,h ).
A burden test adjusted for sex and the first five principal components for the 15 loci revealed highly significant enrichment in rare homozygous, potential compound heterozygous, or hemizygous variants in patients relative to controls (P = 1 × 10 −8 ; odds ratio = 26.6; 95% confidence interval = 7.3–96.6), with 12 carriers among the patients (10.7%, including four homozygotes, one potential compound heterozygote, and seven hemizygotes) vs. three (0.25%, two homozygotes, one hemizygote) among the controls.
Statistical analysis of the asexual parasite prevalence by Chi-square test showed a highly significant reduction of the prevalence with increasing altitude ( χ 2 = 55.74, df =2, p =10 −8 ).
The association of this subset of taxa with the target phenotype was highly significant ( p -value < 10 –8 ).