Excerpts

(iii) Most of the disease LD blocks (67 %) included a single moderately significant disease-trait-associated marker (3E-08 < P < 3.3E-05).

Among the 1509 successfully imputed SNPs in the SNCA locus, the strongest association was with rs2301135 (chr4:90,758,389, p = 5.68 × 10 −5 , OR = 1.40, minor allele C) and remained nearly significant after correction (threshold p < 3.3 × 10 −5 ) using conservative multiple test assumptions of independent SNPs.

For falling number, a nearly significant region was found on chromosome 7B ( p -value = 4.3 * 10 −5 ) with an allele frequency of 89% for the advantageous allele (Figure 5D ).

Moreover, 138 and 176 SNPs were found to have suggestive (moderately significant) association with RFI1 and RFI2 at p < 5 × 10 -5 , of which 124 SNPs have been found to be associated with both traits.

The association findings for these three genes using other methods (O’Brien with GATES and TATES with GATES) are also moderately significant ( P < 7.0 × 10 −5 ), except for MultiPhen with GATES ( P < 0.01).

For the group of girls from the Vrancea region, a negative regression (F0.15 < Fsig 0.69) was obtained, the differences being also quite significant, p -value = 8.12 × 10 −5 .

For elderly male and female subjects, MCW showed moderately significant negative correlation ( r > −0.410, p < 0.0001), whereas FD at molar ( r = −0.076, p = 0.015) and premolar ( r = −0.139, p = 0.019) regions showed significant poor negative correlation with women and no significant association with men.

However, for BOS of the HP, a detached curve of exercised from sedentary mice is visible on the graph and the effect of exercise is quite significant during all the period studied (Fig. 5 f; p < 0.0001; two-way ANOVA).

Simple effects tests to investigate group differences at each time point showed a trend where the highly significant group difference at time zero (described above) became not quite significant after two weeks and then not significant after four weeks (F = 233.5, P < 0.0001; F = 3.29, P = 0.072; F = 0.28, P = 0.60, respectively, with df = 1, 114 for all three tests).

The t-value from the student's paired t-test was 19, indicating a moderately significant difference (p = 0.0001, S).

Among these, CD2 and CD80 , which contain nearly significant ( P <1.00×10 -4 ) SNPs ( rs13904539 , rs13904683 and GGaluGA032608 ) for the antibody response to NDV, belong to the cell adhesion molecules pathway (gga04514), which involves the major histocompatibility complex (MHC) and T cell receptor genes.

Spearman pairwise correlation of antibody inhibition between antigens demonstrates a moderately significant correlation between anti-SSP3 and anti-SPECT1 antibodies (r = 0.62 and p < 0.0001) as well as anti-SPECT1 and anti-CelTOS antibodies (r = 0.65, p < 0.0001), while a relatively weaker correlation albeit statistically significant was found between anti-SSP3 and anti-CelTOS (r = 0.41, p = 0.003) (Fig. 2 b).

Since Mdm2 heterozygosity greatly delays tumor development in Arf -null mice that have both alleles of p53 , the difference in mean survival between p53+/+ and the p53+/− Arf -null Mdm2+/− mice was much larger than their Mdm2 wild-type counterparts and quite significant (p<0.0001, log-rank test; Fig. 2B , Table 1 ).

For example, the EPA% change between the EE and the TG supplements was statistically significant for females, but not quite significant for males (p-value of <0.0001 and 0.0693, respectively).

One study reported a significant difference (MD: 25; 95% CI: 18.16–31.83; P = 0.0001), 27 , 30 and another found a moderately significant benefit (MD: 10.2; 95% CI: 5.91–14.48; P = 0.0001). 27 , 30 Two studies showed no significant differences ( P = 0.1622 and P = 0.2223, respectively). 26 , 36 Physical Well-being of the Chest The results were heterogeneous.

The difference in AGLA expression by FA concentration was quite significant (F (5,12) = 20.58, p < 0.0001).

In addition, Spearman’s correlation analysis showed a moderately significant association between 2-methylbutyric acid and CHD development ( r = 0.5037, p = 0.0001).

These correlations were, however, quite significant at occipital electrodes: (meditation—O1, r = 0.77, P = 0.0001, O2, r = 0.71, P = 0.002; control—O1, r = 0.79, P = 0.0001, O2, r = 0.75, P = 0.001.

Previous GWAS studies in East Asian populations (specifically in Korea) have investigated the genetic factors influencing the albumin-to-globulin ratio and identified two genome-wide significant signals ( p < 5 × 10 −8 ) along with 36 moderately significant signals ( p < 1.0 × 10 −4 ).

The authors claimed that survival decreased by 0.6%/d and pelvic control decreased by 0.7%/d for each additional day of treatment beyond 55 days for all stages of disease. Similarly, a study conducted by Lanciano et al 9 demonstrated a quite significant decrease in survival ( p = 0.0001) and pelvic control ( p = 0.0001) as the OTT increased from less than 6, 6 to 7.9, 8 to 9.9, and greater than 10 weeks.

There were moderately significant positive correlations between VF and MAF [right eye (r s = 0.631, p = 0.0001), left eye (r s = 0.633, p = 0.0001)] and BAF (r s = 0.580, p = 0.0001). 4.

In each group, the mean IOP decreased significantly after Needling, except in the NPDS-Phakic group, which was nearly significant (Phaco-NPDS p<0.0001, NPDS-IOL p<0.0001, and NPDS-Phakic p=0.06).

The linear regression analysis of the hospital stay relative to operator experience was quite significant statistically (p<0.0001) ( Figure 5 ).

The CaG(Pol/Ag) nanomatrices synthesised by two different methods has shown quite significant ( p < 0.0001) anti-cancer activity in increase concentration dependant manner.

Pearson's correlation analysis revealed a moderately significant relationship between soil respiration and soil temperature at 5 cm depth (0.5936; p < .0001), 10 cm depth (0.5046; p < .0001), and air temperature (0.4684; p < .0001), suggesting that the R s tends to increase with soil and air temperatures.