Barely Significant

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514,629 sentences

highly significantP < 0.00010.0× alphaqualifiedgold
Survival analysis for this alteration showed that the difference between wild-type (WT) and NOTCH1 deletion patients was highly significant for both PFS (mPFS: 1.40 vs. 7.83 months; HR = 51.00, 95% CI: 4.80–540.00; P < 0.0001) and OS (mOS: 4.07 vs. 38.30 months; HR = 1 × 10 10 , 95% CI: 0-infinity; P < 0.0001) (Fig. 3G, H ).
highly significantP < 0.00010.0× alphaqualifiedgold
A significant increase in IgG immune response was observed in infected mice groups; specifically, the wild-type mice exhibited highly significant serum IgG response (>1,000-fold) to P. gingivalis ( P < 0.0001) and T. forsythia ( P < 0.0001), TLR2 -/- and TLR4 -/- mice showed significant IgG response to F. nucleatum ( P < 0.0001) and P. gingivalis ( P < 0.0001) (>90-fold), and TLR4 -/- mice had a robust level of IgG response to P. gingivalis ( P < 0.01) (>700-fold) ( Fig. 1D1–3 ).