Compared to sham-NT piglets, HI-NT piglets had a highly significant decrease ( p < 0.0001) in the ratio of normal-to-total neurons ( Supplementary Material Figure S10B ) and a highly significant increase ( p < 0.0001) in the ratio of ischemic-necrotic-to-total neurons ( Supplementary Material Figure S10A ).
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This difference was highly significant (p<0.0001).
Results: The increase in CD4 cell counts was extremely significant ( P < 0.0001).
Nevertheless, the reduction of phagosomal PtdIns4P was highly significant ( p < 0.0001; Figure 6F ), implying that PI4K2A is at least partly responsible for the reformation of PtdIns4P in late phagosomes.
A highly significant interaction of age*genotype was found for all regions investigated ( p < 0.0001), supporting an age-dependent increase in [ 18 F]-AV45 uptake in TASTPM mice.
Acetic acid A highly significant effect was observed due to species (3wAN: F 1,4,2,22 = 9.9, p < 0.0001), with little to no effect on U. intestinalis and the largest effect seen in P. palmata .
As shown in Table 2 , the model was found to be highly significant (F = 246.07, p < 0.0001), indicating that the variability in the response was well explained by the fitted regression equation.
Although the DDH group was small, we still believe that the findings are valid due to the highly significant P < 0.0001.
There is a highly significant correlation (P<0.0001) between the reduced number of DCs and delay in treatment initiation.
For SFTPA2, expression increased 5.13-fold in the severe group compared to the asymptomatic COVID-19-positive patient group and 50.02-fold compared to the mild group, both changes being highly significant ( p < 0.0001).
Quantitative real-time polymerase chain reaction revealed a highly significant downregulation of MDM4 mRNA in tumor tissue compared to control tissue ( P < 0.0001), a finding confirmed by western blot on a subset of 20 tissue pairs.
Results (a) Comparison of the modes and magnitude of skull shape diversification in Darwin's finches and Hawaiian honeycreepers Morphometric analyses in which the more-inclusive landmark datasets were employed (using the final set of 15 landmarks which allows the extinct Hawaiian honeycreeper species to be analysed) on Darwin's finches, Hawaiian honeycreepers and their respective outgroups, reveal a highly significant degree of allometry ( p < 0.0001), which explains 12.6% of the variation in shape of the skull (electronic supplementary material, table S5).
As shown in Additional file 2 , overall, a highly significant positive correlation was found between gene and protein expression of TLR8 ( r = 0.86, P < 0.0001).
Results of multivariate analyses showed highly significant effects of flow [Pillai’s V = 0.579; F(3,255) = 116.9, P<0.0001] and of speed [Pillai’s V = 0.367; F(12,771) = 8.95, P<0.0001].
2 ) independent hairpin sequences had the same effect, each showing a highly significant reduction in cell viability upon treatment with 1 μM PD0325901 compared with DMSO treatment (two-sided t -test, P <0.0001, Fig. 1f ).
Results ICount analysis After generating calibration curves using both methods, we found that the P -values of the regression lines were highly significant (Y micro = 0.87x micro + 3.02; R 2 = 0.965, P < 0.0001 and Y macro = 0.59x macro + 69.74, R 2 = 0.965, P < 0.0001).
The differences between R5 and non-R5 groups were highly significant in all 3 cases (p<0.0001).
A 2 × 2 contingency analysis comparing the groups was highly significant (Chi-square = 25.75, df = 1, p < .0001, Phi = .30).
The difference between total mortality of treated and control groups was highly significant (P= 0.0001) ( Jalilnavaz et al. 2016 ).
Gene set enrichment analysis identified a highly significant overlap of transcriptional markers of intestinal stem cells (chi‐squared test with Yates's correction, P < 0.0001; Munoz et al , 2012 ) between the gene lists, demonstrating elevated expression of some members of the intestinal stem cell signature following Huwe1 deletion.
The model explained 77.8% of the total variation in the observed number of eggs per snail which was highly significant (PROC NLIN: F 3,729 = 853.8; P < 0.0001).
The difference in the incidence of post TIPS HE between the patients with or without sarcopenia was highly significant (p < 0.0001).
Further we have observed a decreasing trend in the level of Tregs in children born to both infected and uninfected mother as compared to the cord blood (p <0.0001 for CFA+ve and p < 0.0001 for CFA-ve).
The negative association between the minimal doubling time and the average number of prophages per host genome was highly significant in this much larger data set (Spearman's ρ =−0.36, P <10 −4 ), independently of host genome size ( Supplementary Figure S7 and Supplementary Table S2 ).
Among the genes associated with auditory abnormalities, in the cellular component domain, the most strongly enriched term was cytoplasm, with 67% of annotated genes and a highly significant adjusted p ‐value p < 0.0001.