Excerpts

Shape ANOVA revealed a highly significant main effect of genotype on ventricular shape (procrustes ANOVA: F = 9.29, p = 0.0001) and a significant induction × genotype interaction ( F = 2.45, p = 0.0157), indicating that the impact of PKN2 loss on heart shape depends on when the knockout was induced.

Results indicated a highly significant main effect of time, F = 96.20, P<0.0001.

By week 1, the Col/Cs/A-PRF group showed a significant reduction in BMD (~ 650 HU) compared to the C group (~ 750 HU), with a highly significant difference ( p < 0.0001).

Highly significant effects of genotype on female night sleep were present ( P <0.0001; S12 Table ), as well as significant pleiotropic effects on all sleep traits ( S12 Table ).

All comparisons were statistically significant at P ≤ 0.0001, except DILC, which remained highly significant ( P = 0.0001).

The PERMANOVA showed a highly significant difference between the three populations ( F = 8.79, DF = 2, P = 0.0001) as well as for each pair of populations ( S2 Table ).

We found highly significant positive correlations between the identity levels of allergens and the representative helminth (r = 0.70, P<0.0001), protozoan (r = 0.64, P<0.0001) and fungal (r = 0.47, P = 0.0011) organisms suggesting that a conserved protein allergen in HPF is also conserved to a similar level in human.

(22) Not surprisingly, the t ‐test results were highly significant ( p < 0.0001 ).

An unpaired t-test revealed a highly significant difference in TL between the two groups ( t 31 = 6.83, p <0.0001, Figs. 1 and 2 ).

We found a highly significant correlation between chronological age and epigenetic age for both baseline (V1) and week 12 (V2) calculated using the Hannum (V1: p < 0.0001, R = 0.74; V2: p < 0.0001, R = 0.77; Fig. 2 A) and Horvath (V1: p < 0.0001, R = 0.69; V2: p < 0.0001, R = 0.70; Fig. 2 B) clocks.

This performance is further strengthened by highly significant global p -values in 2LOmb results from all three interaction problems ( p < 0.0001) and the presence of a SNP in common among some or all pairs of two-SNP units in the three- and four-locus interaction problems.

RNL lower than 0.650), compared to the controls (statistical differences highly significant, p < 0.0001 for Pt-3, Pt-5 and Pt-8 and p < 0.001 for Pt-4) ( Figure 6 ).

We performed a sensitivity analysis to test the reliability of the meta-analysis, which showed that removing any one study would not lead to a marginally significant difference between the two groups ( P < 0.0001; Supplementary Figs. 35–36 ).

LACE score was highly significant as a predictor of readmission (p<0.0001), with an AUC of 0.773 (95% CI 0.768 to 0.779) and R 2 of 0.180.

Two‐way ANOVA indicated a highly significant effect of time ( F 5,35 = 13.0; P < 0.0001), but no significant effect of treatment ( F 1,7 = 5.15; P > 0.05).

The paired differences were statistically insignificant all the groups on mesial aspect; except for the distal aspect of G1S1 and G2S1 which was found to be highly significant (p<0.0001).

Controlling for these potential effects, the method remained highly significant (P < 0.0001).

tabaci isoline on virus titer in thrips The main effect of TSWV isolate on virus titer per thrips was highly significant [F = 8.6, df = (3, 93), P < 0.0001] (Fig. 2 ), whereas the main effect of T. tabaci isoline [F = 2.3, df = (3, 93), P = 0.0820] (Fig. 3 ) was not.

Quantitative HI suv demonstrated a highly significant correlation with visual heterogeneity ( r = 0.5, p < 0.0001).

Highly significant correlations generally exist between the various markers (p<0.0001), with a slightly lesser significance between MLANA and MITF (p = 0.005), with the exception being between MLANA and TYR markers, where no statistical significance was found (p = 0.11).

Again, when cell lines were classified in regards to their LumA or TNBC status, the differences obtained were highly significant ( p < 0.0001).

Differences between diameters and heights in the two groups are extremely significant (Student's t test; P < 0.0001 in both cases).

5 and by applying a CADM test reveals a highly significant congruence among the topologies ( P < 0.0001), which further emphasizes tight links between the evolutionary histories of mitochondria and Wolbachia .

A PERMANOVA on unweighted UniFrac distances for replicate samples stored in RNAlater revealed that individual horse was highly significant (F 29,65 = 2.55, r 2 = 0.67, p < 0.0001) and day of sampling less so when controlling for individual horse (F 6,65 = 2.55, r 2 = 0.06, p = 0.0334).

Interestingly, we have observed a highly significant decrease in mtDNA copies in SLE patients compared to healthy controls ( P < 0.0001).