The univariate analysis of factors associated with SFV infection showed a highly significant association with male sex (p<10 −4 , χ 2 = 24.6), with the Pygmies (p<10 −4 , χ 2 = 20.85), hunting (p<10 −4 , χ 2 = 233.5), apes (p<10 −4 , χ 2 = 446.2), bites (p<10 −4 , χ 2 = 267.1) and wounds to the upper part of the body.
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For the MGL-expressing HEK293-cells, we observed a highly significant (P<0.0001) specificity for GalNAc-BSA ( Figure 1D ).
At both time points, highly significant increases in STAT6 phosphorylation (pSTAT6) (Fig. 3 b,c), as well as pSTAT3, was detected in both T cell subsets (p < 0.0001 for all) (Fig. 3 d–f).
Additionally, CCL3 and CCL20 play crucial roles in angiogenesis and immune cell recruitment, supported by highly significant differences in their levels ( P ≤ 0.0001).
Due to the large number of data sets in each population, both correlations were highly significant (p<0.0001), though data points are not fully independent.
HR exhibited a highly significant difference ( p < 0.0001) between Phase 4 (90.6 ± 11.8) and Phase 6 (82.4 ± 14.6).
All effects and interactions were highly significant ( P < 0.0001, F -test; n = 10,612 in total).
A recent study found a highly significant correlation between the increased expression of miR-125b and CRP/IgE levels (r = 0.86/r = 0.68; p < 0.0001) in asthma patients, indicating the potential relevance of this miRNA for particular asthma phenotypes.
A Spearman's correlation applied to this collapsed data confirmed a highly significant negative relationship (rho = −0.1131, p < .0001).
That approach resulted in similar results as in the linear models described above, with highly significant associations between low BDE-47 concentrations and the genotypes with MAF in the 0.36-0.45 range (all p = 10 -4 to 10 -6 )(data not shown).
Statistical analysis using two-way ANOVA with Bonferroni post-test on a pairwise comparison of the profile of the unfertilized oocyte with mRNA profiles collected at different time points after fertilization revealed that the correlation between segment and mRNA level is extremely significant ( P < 0.0001), but that there is no effect of fertilization and time following fertilization ( P ≈ 1).
Overall, primary efficacy analysis showed the difference in terminal hair density change at 26 weeks from baseline between lasercomb and sham treatment was highly significant ( p < 0.0001) in both female trials (Fig. 2 a, b).
We also confirmed PAR1 expression in samples from our patients using immunofluorescent staining for PAR1 present in the surface of the cells (Figure 1c ), and found 30 patients out of 50 high grade breast cancer patients included in this study (70%) express PAR1; highly significant when compared with the rest of the group (P = 0.0001).
A highly significant increase ( p < 0.0001) of 7.29 and 10.80 times in CAT activity as compared to control was observed in 36 and 44 μg/ml treated cultures, respectively ( Figure 6C ).
During the breathing exercises, there was a highly significant initial difference in heart rate response between hyperventilation and diaphragmatic breathing (p<0.0001).
The effect of regime on development time was large and highly significant ( F 1,265 = 66.75, P < 0.0001), with exposure to constant temperatures reducing developmental period for all possible regime x temperature x sex treatment comparisons ( Fig. 5 ).
All correlations remained highly significant ( P <0.0001) after controlling for ethnicity, socioeconomic status, birth weight, placental weight, gestational age at delivery, parity, tobacco smoking status (0, 1–10 or >11 cigarettes smoked per day), labor onset, labor induction, labor duration, oxytocin administration, tocolytic administration, antenatal steroid administration, APH, PTB, and PROM in multiple regression analysis.
Unpaired t-test showed that there was highly significant difference between patients and controls in age, weight, and BMI ( P <0.0001) only as shown in Table-I .
Despite the strong Calcein background fluorescence we measured an increase in mean values of 13.0% (239 Nef vs Y 28 F; n = 22) and 14.1% (239 Nef vs Y 28 F; n = 22) which is highly significant (p < 0.0001).
Analysis of all completers and withdrawals showed a strong trend over time ( p < 0.0001), and a difference in rate of change between groups (delayed-image: −0.50 kg, early-image: −0.27 kg, p = 0.0008).
For both tau and NfL there were highly significant differences across diagnostic groups including HCs (Kruskal-Wallis, p=0.0001).
The need for antibiotic therapy after 48 h post-procedure was significantly higher in patients who underwent open laparotomy (71%) and conventional laparoscopy (45.4%) compared to TSILA (25.3%), with a highly significant association in the general analysis ( p < 0.0001).
The combination between SCF and LRG1 showed highly significant difference in CRC patients compared with benign, healthy subjects, and among CRC groups (treated and non-treated) ( p < 0.0001).
Testing this distribution against the null hypothesis, that the percentage of suicide attempts is the same for all seasons, points to a highly significant seasonality effect (Chi-squared test, χ 2 = 53.803, df = 3, p < 0.0001).
A highly significant positive correlation was observed between p-AKT and Rictor expression in feline carcinomas ( p = 0.0001).