Excerpts

As would be predicted, a highly significant negative correlation was also observed between PARP activity and NAD + levels ( Fig. 6B , r = −0.638; p = 0.0003).

When categorizing samples into five groups we found an overall highly significant difference (p=0.0003) in median %ddcfDNA.

From post hoc comparisons, no significant comparisons within genotypes (both within G/G and within G/A) are observed, while highly significant is the comparison between G/G and G/A genotypes ( p < 0.0003), thus highlighting that the highest HbF induction was found in G/A rs368698783 genotypes. 2.2.

T-test comparison of SA versus UD means for discriminant function score, paired by clinician, replicated the overall results with a highly significant mean difference 1.77 points (p = 0.0003).

One-way ANOVA demonstrated a highly significant difference in mean age across the groups (F = 18.42, p = 0.0003), indicating that age distribution varied significantly among the study populations.

At the 12-month follow-up, the difference was highly significant, with an OR of 15.51 (95% CI: 3.57–67.36); p = 0.0003 for four studies [ 5 , 17 , 18 , 20 ] strongly favoring the inverted ILM flap method for anatomical closure.

Differences across sites were highly significant for DeepARG results (Kruskal-Wallis, P = 0.0003) with pairwise comparisons showing that SSP had higher relative abundances than CSP (Wilcoxon rank-sum test, BH-corrected; P = 0.0004) and CPT (Wilcoxon rank-sum test, BH-corrected; P = 4.8 × 10−9).

There was a highly significant subretinal treatment effect on ERG amplitudes collectively at 7–9 months post-injection (p = 0.0003).

The difference of ECVM-treated (n = 9) versus control (n = 11) eyes was still highly significant (p = 0.0003, Mann Whitney test; Figure 2 C).

High) was 4.86-fold, and was highly significant ( p -value = 0.0003).

We sought replication in independent samples for this marker and found highly significant association ( p = 0.0003) in 3 Caucasian replication samples.

Regressing the ADOS severity score on the percentage of MSA in the retelling task produced a high value for the coefficient of determination ( R 2 = 0.85) and highly significant goodness of fit results ( f ‐ p value = 0.0003).

The test for overall effect is highly significant (Z = 3.61, P = 0.0003), and heterogeneity is not applicable due to the single study analysis.

Thirty-two molecules did not show a significant association with any measure of glucose and insulin homeostasis, although 5 showed associations with ≥1 measure of glucose and insulin homeostasis that approached significance (defined as: 1.0∗10 –4 > P > 3.0∗10 –4 ; Supplemental Table 5 ).

A positive signal was detected in 11/14 samples, and only 1/14 among negative controls, with a highly significant statistical difference (p = 0.0003, Fisher’s exact test), based on a blind assessment by a naïve observer.

Analysis of the data using the additive model also showed a highly significant association (OR = 1.4 per allele [95% CI 1.2–1.7], p = 0.0003; Table 2 ) indicating that having more A alleles was significantly greater in WNV-positive individuals than in controls.

A Kruskal–Wallis test revealed highly significant differences in yield among climate zones (H = 19.119, df = 3, p = 0.0003) ( Table 7 ).

However, pmax decreased across gestation in overweight/obese women, whereas it increased for normal weight women ( Figure 2a ); this difference in rate of change between groups was highly significant ( P =0.0003).

In the construction of the final model (AIC = 154.2), it was found that the type of urban planning is relevant to explain the abundance of rabbits, obtaining a highly significant model (F 6,29 = 6.05; p = 0.0003) that explains somewhat over 46% of the variability observed in the data (adjusted R 2 = 0.464).

Results: MI was found to be varied, and the differences were highly significant among Group III and IV ( P = 0.0003) and Group II and IV ( P = 0.0007), and significant difference was found between Group I and Group II ( P = 0.0113).

Spermatozoa treated with TTO showed a decreasing trend for TotM ( Figure 3 A) already at 0.4 mg/mL, statistically appreciable only from 0.8 mg/mL ( p = 0.0003).

In contrast, two other studies demonstrated a "highly significant" correlation using the Spearman rank correlation test ( P > 0.0003 and P > 0.0001, respectively) [ 18 , 20 ].

However, the slope of a linear regression analysis of the Schachter study [ 54 ], which had reported the IPD, indicated that vitamin C’s relative decrease in FEV 1 decline was highly significant: 55% (95% CI: 32 to 78%; P = 0.0003) [ 55 ].

This study reported a highly significant association between being exposed to multiple antibiotic courses before three years of age and being part of the NDD group (p = 0.0003).

The IRC reflection parameters and FSRTF during demineralization showed a trend of decrease (IRC: R = 0.95; p = 0.0003, FSRTF: R = 0.76; p = 0.0286), while the backscattering parameter AIB increased (R = 0.81; p = 0.0148) and FSAB showed an oscillatory behavior with no defined trend (R = 0.23; p = 0.5837), as shown in Fig. 2 .