Excerpts

The highly migratory cell lines (BxPC-3 and Panc-1) presented the highest oxygen consumption rate (OCR) ( Figure 1 E), and a highly significant correlation was observed between myoferlin abundance and basal OCR (r = 0.9997, P = 0.0003). 2.2.

Difficulty in breathing was the second most common presenting symptom reported in 32 patients (24.62%) with an incidence of only 2.70% in Group A while 33.33% in Group B and was therefore, found to be highly significant ( p value = 0.0003*). 5.41% cases in Group A did not have any symptoms while in Group B, 19.35% were asymptomatic ( p value = 0.046*).

Variants in MT-CYB were nominally significant (p = 0.0003): MT-CYB (mitochondrial cytochrome b) is part of the mitochondrial respiratory chain, and essential for Complex III formation.

The contrast testing treatment effect over time H 0 : ( α 4 , α 6 , α 8 )′ = (0, 0, 0)′ is highly significant (Wald-type robust p = 0.0003), indicating that the SafeTalk intervention affects UAVI count.

However, in the SN ipsilateral to lesion, there were highly significant increases in extracellular DA in the SN after K + -infusion in striatum (F(1,11) = 27.9, p = 0.0003; Figure 6 F), with extracellular DA increasing by ~7-fold within the first 20 min.

Hazard ratios of revision surgery were higher with lower final score or less improvement in Mayo hip score at 2-years and borderline significant/non-significant at 5-years, respectively: (1) score ≤55 with hazard ratios of 2.24 (95 % CI, 1.45, 3.46; p = 0.0003) and 1.70 (95 % CI, 1.00, 2.92; p = 0.05) of implant revision subsequently, compared to 72-80 points; (2) no improvement or worsening score with hazard ratios 3.94 (95 % CI, 1.50, 10.30; p = 0.005) and 2.72 (95 % CI, 0.85,8.70; p = 0.09), compared to improvement >50-points.

1 C) showing a highly significant linear correlation (Pearsons r = 0.9963; 95 % CI = 0.9429 to 0.9998; P = 0.0003) ( Fig. 1 D).

3 , LLMs consistently yield positive assortativity across all features and models, with results highly significant ( P < 0.0003 , t -tests with Bonferroni correction).

The occurrence of co‐loss of ARID1A and PTEN was highly significant and nonrandom ( p = 0.0003, Fisher's exact test, two‐tailed).

These two analysis time windows produced highly significant differences in proportion of dwell time on the eyes (t(30) = −4.06, p = 0.0003, two-tailed), nose (t(30) = −4.95, p = 0.000027, two-tailed), and “other” AOIs (t(30) = 12.90, p = 9 × 10 −14 , two-tailed).

In contrast, the group of metastatic primary hLT (pT × N2) showed a highly significant difference (mean CD9P-1 index±s.e.m.: 2.179±0.436; P =0.0003; 95% CI=−1.938 to −0.6739) compared with the group of primary hLT (pT × N0) ( Figure 2B ).

Correlation analysis of pERG amplitudes between OS and OD eyes using data from both groups revealed a robust and highly significant relation between eye pairs, as well as a distinct separation between the EAE group from naïve controls ( Fig. 2 D; r = 0.64; P = 0.0003).

When Gas6 was used as dependent variable, sAxl was the only highly significant independent variable ( P < 0.0003).

The increases in temperature were highly significant (repeated measures anova controlling for plot: F 1,6 = 59.03, P = 0.0003) but did not affect soil moisture (treatment: F 1,4 = 0.08, P = 0.7880; treatment × time: F 37,148 = 0.74, P = 0.8557) in the period when the heaters were turned on.

Further to this, the promoter SNPs had highly significant associations with pHULT ( p = 0.0003) in the Large White breed, an association which was not observed with I199V .

In vascular surgery, the difference in the glitch rate between site E (mean of 6.3 glitches/hour) and site D (mean of 10.5 glitches/hour) was highly significant, p=0.0003.

The results from the model indicated that there was no significant effect of treatment on the F: B ratio in the goat milk microbiome (p value = 0.67068), whereas the effect of timepoint was highly significant (p value = 0.000305).

One-way ANOVA showed highly significant group effects for both Tb.Th (F(2,6) = 41.32, p = .00031) and Tb.Sp (F(2,6) = 23.77, p = .00141).

The haplotype association studies of 268 cotton cultivars ( Fang et al., 2017 ) with marker K222 also showed an extremely significant association with an FS trait at Korla, Xinjiang province (p value = 3.13 × 10 −4 , Student's test), Nanjing, Jiangsu province, and Anyang, Henan province, three cotton-growing regions in China ( Figures 1 D and S2 C).

Evidence for recombination was supported by highly significant PHI test values ( P = 3.17E−4; Fig. 2 ).

Statistical analysis by two-way ANOVA revealed a highly significant interaction between the effects of the Vav-Cre and Syk flox/flox mutations ( p = 0.00032 and 0.00003 for males and females, respectively), indicating that Cre-mediated deletion of Syk in Syk Δ Haemo mice strongly increases trabecular bone mass.

The R and Rh samples showed highly significant species richness compared with the BK samples ( p = 3.23E-04 and p = 5.91E-06, respectively), whereas no significant differences were observed within each sample type.

The difference between heterotrophic and autotrophic free energy of the 5′UTR was highly significant ( P = 3.27 × 10 − 4 ) with median values of − 2.1 kcal/mol and − 3.4 kcal/mol for increased and decreased TE, respectively (Additional file 12 : Figure S2b).

2d ), showing a highly significant association between ecDNA in Barrett’s oesophagus biopsies and progression to EAC (Fisher’s exact test, P = 3.3 × 10 −4 , one-sided). ecDNA can arise in high-grade dysplasia The design of the longitudinal case–control FHCC study enabled the timing of ecDNA development in Barrett’s oesophagus segments to be determined in patients with a cancer outcome.

These data showed a highly significant difference ( P = 0.00033) in the reduction of plaque diameter caused by the deletion of Vhs between Caco-2 cells (2.123- ± 0.096-fold) and tetherin-depleted Caco-2 cells (1.588- ± 0.070-fold).