Barely Significant

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highly significantp < 0.0010.0× alphaqualifiedgold
Independent utility analysis of route of administration Analysis of administration route controlling for disease classification injection remained highly significant (β = − 0.093, p < 0.001), indicating that dislike of injections is not solely due to disease severity (Table 3 ).
highly significantP-value = 0.0010.0× alphaqualifiedgold
Results This study found that there is an effect of coronavirus infection on the bone strength measured by the Mean of the OPG level, which was found to be highly significant in the serum of post-COVID-19 patients when compared with non-COVID-19 subjects (P-value = 0.001), but the Mean of ACE-2 level was statistically non-significant between the two groups (P-value = 0.13).
highly significantP < 0.0010.0× alphaqualifiedgold
Quality of Life, Utility Weights, and QALYs Within both treatment groups, we observed highly significant improvements ( P < 0.001) in the overall scores in the ICIQ-LUTSqol at 4 months (mean change Internet 4.8 [SD 6.1], Postal 4.6 [SD 6.7]), and at 1 year (mean change compared with baseline; Internet 5.3 [SD 6.4], Postal 4.5 [SD 6.4]).
highly significantP < 0.0010.0× alphaqualifiedgold
A chi-square test comparing the frequency of A-IGH and B-IGH usage across the different B cell subsets showed a highly significant difference ( P < 0.001), indicating a strong association between B cell phenotype and locus usage, strongly favoring the use of B-IGH locus BCRs in differentiated B lineage cells that have not undergone class switching.
highly significantp < .0010.0× alphaqualifiedgold
The abundance of Chloroflexi had a markedly negatively relationship with available potassium ( r = −.99, p < .001) and total carbon ( r = −.82, p = .001), and the Bacteroidetes exhibited a highly significant positive correlation with available potassium ( r = .90, p < .001) and total carbon ( r = .81, p = .001), then Nitrospirae ( r = −.95, p < .001) were significantly negatively correlated with soil available potassium.
highly significantp < 0.0010.0× alphaqualifiedgold
GraphPad Prism version 8.0 (CA, USA) was used for the analysis, and significant differences were assessed using one-way ANOVA followed by Tukey’s post-hoc test (significant at p < 0.05, very significant p < 0.01, and highly significant p < 0.001).
highly significantP <.0010.0× alphaqualifiedgold
When using the 80th percentile cut-off point (ie, abnormal or borderline range), 42 (93%) children were above the cut-off point at baseline, while the respective figure at the 6-month follow-up was 23 (51%) children, indicating a highly significant change ( P <.001).
a decreasing trendP = 0.0010.0× alphagold
After controlling for these effects, I found that mean hemoglobin concentrations differed significantly between urban zones ( F 1,25 = 3.23, P = 0.036), showing a decreasing trend from the most urbanized areas to the natural-like habitats in the suburbs (contrast analysis: F = 13.00, df = 1, P = 0.001; Figure 3 A).
highly significantp < 0.0010.0× alphaqualifiedgold
Quantitative analysis revealed highly significant differences in spermidine levels between OIPN and CONT groups across all nutritional strata: in the whole cohort ( Figure 3F , p < 0.001), the malnutrition group ( Figure 3G , p < 0.001), and the well-nourished group ( Figure 3H , p < 0.001).