Excerpts

Mantel tests of pair-wise geographic distances and genetic distances, measured as F ST or as percentage of allele differences among populations, detected highly significant correlations (0.59 < r < 0.82; P < 0.001; Figure 1 B) accounting for up to 67% of the variance.

This difference was highly significant (OR = 3.7, p value < 0.001).

However, the r values of the present study are highly significant with P <0.001.

Salinity accounted for the largest proportion of variance, with a sum of squares of 8750, representing 36.8% of the total variation, and exerted a highly significant effect on plant growth (F = 95.4, df = 1,93, p < 0.001).

For the absolute peak area values, the treatment was highly significant (PERMANOVA; pseudo- F = 30.019, p = 0.001), with a component of variation of 4.6922 (square root = 2.1662) and a clear separation between the treatment groups along PCO1, which explained 77.3% of the total variation ( Figure A).

A significant effect of the co-culture conditions revealed that culture of hBM-MSCs in tumour spheroids with MDA-MB-231s and T47Ds had a highly significant effect on the spheroid size of hBM-MSCs across 5 days (hBM-MSCs alone, +MDA-MB-231s or +T47Ds; F (2,6) = 357.792, p = 0.001).

Comparable highly significant ( p < 0.001) positive dynamics in the EF was observed in both groups after 6 months from the start of the treatment and by the end of the study ( Figure 3 ).

Moderating effect of indecisiveness on rumination and depressive symptoms Utilizing a robust Wald test, the overall model fit was highly significant, R 2 = 0.54, χ 2 (9) = 268.46, p < 0.001.

Log–log regression further revealed a highly significant allometric exponent (β = 0.47, p < 0.001), indicating sub-isometric scaling, whereby proportional investment in stone mass declined with increasing fruit size.

One-way ANOVA followed by Tukey HSD post-hoc tests confirmed highly significant differences (p < 0.001) in all metabolic markers across clusters ( Figures 2D–J ).

The Genetic Differentiation among Clam Populations The overall genetic differentiation among these populations was moderate but highly significant (global F st = 0.066, p < 0.001),indicating the existence of the genetic heterogeneity among populations.

Though it is associated with all three finger patterns, branched lip print associated with arch finger print is highly significant ( P =0.001) followed by loop finger print pattern ( P =0.005) and whorl finger print pattern ( P =0.006).

In fact, among the three populations, extremely significant differences were found for CYP4C67 [ F ( 2 , 27 ) = 21.056, P < 0.001], CYP4C68 [ F ( 2 , 27 ) = 14.979, P < 0.001], CYP4C70 [ F ( 2 , 27 ) = 28.084, P < 0.001], and CYP4DB1 [ F ( 2 , 27 ) = 19.673, P < 0.001].

Brown pod rot ( Phytophthora spp.) was the second most frequently reported constraint, exhibiting highly significant spatial variation ( P < 0.001).

Notably, the observed shifts in down- and upregulated parameters were highly significant for both, brain and liver tissue ( p ≤ 0.001) (Fig. 2 C), and highly significant changes exist by comparing brain with liver tissue utilizing the Fisher ́s exact test.

We found highly significant correlations (from r = 0.63 to r = 0.89, p < 0.001) between estimated percentages of symptomatic plants in independent trials (data not shown).

There was a highly significant main effect of Group, F (2, 49) = 44.520, p < 0.001, η p 2 = 0.645, as scores decreased with increased attention impairment (see Figure 2 ).

The difference between the means of mean sedation score, emergence behaviour score, mean emergence time was statistically highly significant ( P <0.001).

For the non-small cell lesions that comprised a majority of the cancer patients, there was a highly significant (P<0.001) increase in the value of the LEBS marker.

The F -test with true value 0 (25.24, both for individual measurements and for mean measurements) was highly significant ( p < 0.001).

This creates a “shunting inhibition” effect: the leaky membrane creates a low-resistance path that prevents the accumulation of charge necessary for threshold depolarization. Statistical analysis ( Figure ) confirms that while peak current magnitude shows high variance ( p = 0.110), the increase in hysteresis energy is highly significant ( p < 0.001).

The resistance rate of cephalexin showed a highly significant increasing trend from 2013 to 2021 ( P < 0.001) (Fig. 2 B).

The model suggested an increasing trend in sCr levels during pregnancy in cases who later developed preeclampsia ( p < 0.001; Supplementary Fig. 1).

Results Behavioral data One-way ANOVAs revealed a highly significant (p < 0.001) effect of load (low, medium, high) on reaction time (RT; F (2, 90) = 44.7) and accuracy ( d’ ; F (2, 90) = 70.5).

Compared with 1 patient (5.9%) in the CWD group and 0% in the LNPWT group, five patients in the HNPWT group (42%) presented with distal ischemia, with a highly significant difference between the groups ( P = 0.001) (Figure. 1 ).