“a clear trend”

For these experiments, the medium concentrations of hypericin (0.5 and 1 μM) were used based on a clear trend of decreasing HIF protein levels in hypoxia.

In addition, we investigated other brain proteins containing a mannose-6-phosphate group 42 to test whether we could see a clear trend in the level of these cargoes in LE/Lys of JNCL patients compared to controls.

Nevertheless, a clear trend consistent with previous reports was observed, which may clearly aid in the management of early local recurrence of glottic cancer using salvage TLM.

The background permittivity ε ∞ and the upper cut-off frequency ω max do not show a clear trend with annealing temperature and are not important for further discussion of the physics of our materials.

Although there are no differences in EOR and visual outcomes between the two groups, there was a clear trend in the EEEA group to obtain a better outcome.

In a large patient cohort study ( n = 7505) with 5 year FU, a clear trend was observed with the per-patient 5 year cumulated number of inpatient days decreasing by 6% per annum after adjustment for age at diagnosis, parental mental health, and household income.

Cardiac performance showed no significant differences, however, there was a clear trend toward lower heart rate in the iREBOA group during balloon deflations with no difference in cardiac output (Fig. 3 b, c, e).

However, a clear trend cannot be inferred from these results.

Significant differences were not seen, but a clear trend was recognizable.

IMD Deciles showed a clear trend – more deprived areas (IMD Decile 2 and 3) remained busier than the average during the lockdown, whereas less deprived areas (IMD Decile 8–10) had more decline in activities.

In recent years, there has been a clear trend toward using modern molecular cytogenetic methods in insect research.

Broad surveys of ant gut microbiota suggest a clear trend that specialists (e.g., herbivores) have increased bacterial density but reduced bacterial diversity in their guts.

Although there was no significance in Caspase3 activation in MKN45 cells, there was a clear trend of upregulated cleaved-Caspase3 expression ( Figure 4E ).

ACE2 and CTSL coexpression showed a clear trend of joint upregulation in males (Fig. 3 D).

However, a clear trend can be reported.

Results Figure 2A charts the number of daily discussion posts on Weibo, indicating a clear trend.

Although there is a clear trend towards miniaturization of dispersive medium-based devices 13 – 16 , there remain clear trade-offs between resolution, device size and cost.

The bioreactors also showed a clear trend with respect to the molar ratio of butanol to butyrate produced.

The only non significant P-value was relative to the production of 1 cytokine by CD8 + Melan-A + T cells, where the 2 patients with percentages higher than the cut-off showed a clear trend of long RFS but were lost early at follow-up ( Figure 4 ).

Basically, it can be said that a decrease in mediator activation, a negative balance, and a clear trend toward stabilization of organ functions make the performance of follow-up operations appear justifiable ( 17 ).

We observed (i) an association between anti-CCP2 positivity at RA diagnosis and VTE risk, including a clear trend towards higher VTE risks with higher IgG CCP2 levels, (ii) an (at least) equally strong association between the number of ACPA fine-specificities and VTE risk, (iii) no specific association with anti-Cit-Fib antibodies or with AMPA targeting carbamylated or acetylated antigens, (iv) an association between IgM RF and VTE risk, and (v) that none of the associations were readily explained by smoking or the HLA-DRB1 shared epitope.

Despite this optimization, MCL could not be demonstrated to significantly induce expression of either Mincle (Figure 3F ) or Dectin‐2 (Figure 3G ), although a clear trend was apparent for Mincle. 3.3 Mincle can be co‐immunoprecipitated with MCL To confirm the association of human Mincle with MCL, we co‐transfected 293T cells with MCL and FcεRIγ, together with FLAG tagged Mincle, Dectin‐2 or DCIR.

The most important finding is a clear trend and a significant decrease of the EGG power after both single as well as repeated administration of rivastigmine.

When stratifying by lead time (time between blood draw and diagnosis), 19 proteins showed heterogeneity in associations ( p het < 0.05, Supplementary Data 8 ) and 11 had a clear trend in the strength of association across categories of lead time ( p trend < 0.05, Supplementary Fig. 7 , Supplementary Data 9 ).

PC2 represent 89% of the explained variance, reflecting a clear trend with the treatment in the direction of PC2 ( Figure 1 A).