“a clear trend”

While 2–3 month APP SAA mice showed a clear trend towards a novelty preference on the OLT ( p = 0.054), 16 month APP SAA mice had a novelty preference score that was no different than chance levels (despite spending similar time exploring the objects, Supplementary Fig, S2 a), suggesting that they were no longer able to remember which object had been moved (Fig. 2 a).

The rates for BARC type 3 to 5 and BARC type 2 to 5 bleeding were not statistically significantly different although BARC type 2 to 5 bleeding showed a clear trend towards more events in the PP-ZES arm (7.0 % vs. 2.9 %; p = 0.054).

These modifications were associated with an improvement of liver stiffness which did not reach statistical significance but nonetheless marked a clear trend towards reduction (12.8 vs. 13.8 kPa, p = 0.055).

6e ); however, there were no significant differences in rate changes between genotypes, despite a clear trend for a slower rate in OsEPF1oeS (Kruskal–Wallis one‐way ANOVA, overall P = 0.056) (Fig. 6f ).

Just at 12 h after the introduction of the nestlet, rTg4510-treated mice were performing not significantly differently than controls, although there was a clear trend to show reduced nesting behavior ( p = 0.0569).

No changes were observed in the adrenal medulla; however, a clear trend of increased NE was observed in the kidney ( p = 0.0570).

The absolute collagen area in the plaque was reduced (−38.3%), and a clear trend toward a lower relative collagen content of the plaque (−23%; P =0.058) was demonstrated in the ONX-0914–treated group (Figure 1 C), indicating a less progressed plaque phenotype upon ONX-0914 treatment.

resin) demonstrated a clear trend towards better hypertrophy (f = 3.833, p = 0.058).

Of note, subgroup analysis of only patients that underwent mitral valve repair ( n = 76) showed a clear trend but not a statistically significant difference between LVEF decrease in BD versus FED (−5.7 ± 8.5% vs. −3.7 ± 7.1%, p = 0.059) ( Supplementary Table S1 ).

Although a clear trend emerged, with women showing lower well-being scores than men, this difference is not statistically significant [ t (372) = 1.89, p = 0.059].

Despite a clear trend in the univariate analysis, high TLG (≥159.2 g) was not significantly correlated with poor OS (P=0.059).

The statistical significance level is not clearly reached here, but a clear trend can be seen ( p = 0.06).

Although we did not find significant changes in ATAD3 phosphorylation or levels in the present LC–MS/MS analysis, there was a clear trend for a decrease in protein levels in NEK10 KO samples (192/178/203 for NEK10 KO samples and 205/228/245 for Parental cells, p = 0.06; Supplemental Table 1).

However, upon careful reading, the results of the Italian TSUNAMI RCT were not completely negative, but showed a clear trend towards efficacy ( p = 0.06) of CCP versus standard therapy in the subgroup of patients with milder (and thus earlier) disease.

In the experienced group, a clear trend toward a reduction in anastomotic complications (21.4% vs 5%; p = 0.06) and severe complications (14.3% vs 6.25%; p = 0.27) was observed, although the differences were not significant.

The analysis showed a clear trend towards increased protein levels GRP78 in neurons of the SNpc; the content of GRP78 increased 1.4 times ( p = 0.06) 3 h after its administration compared with the control ( Figure S4 ).

Additionally, a clear trend of increased AUC ∞ /DW (613.46 ± 220.42 h*ng*kg/mL*mg, p = 0.060) and C max /DW (57.69 ± 22.19 ng*kg/mL*mg, p = 0.067) was also observed for SLCO1B1 DFs + PFs in comparison to IFs + NFs (530.36 ± 223.98 h*ng*kg/mL*mg for AUC ∞ /DW; and 49.59 ± 22.09 ng*kg/mL*mg for C max /DW) ( Table 3 ).

Similarly, the ItchyQoLTM questionnaire revealed a clear trend of itch reduction after 6 weeks with 80% of subjects (12/15) noting decreased itch ( P = 0.06) which became significant after 12 weeks of bleach baths, with 100% of subjects noting improvements in itch (Fig. 1 e).

albicans (partial Spearman P = 0.015, R 2 = 0.57) and a clear trend with Candida genus abundance (partial Spearman P = 0.06, R 2 = 0.46; Fig.

Despite a clear trend in the univariable analysis, a high TMTV was not a statistically significant prognostic factor for OS in the CIT group (HR 2.2, 95%CI 1.0–4.8, p = 0.06).

While the difference in cholangitis was not significant in this analysis, there was a clear trend towards lower cholangitis rates in the PTBS group relative to the EBS group ( p = 0.06).

A clear trend (p = 0.061) toward higher arrhythmia scores was also observed in older males than in females of the same age (Fig. 2 g).

Furthermore, there was a clear trend toward longer LRRFS [HR 0.497 (95% CI 0.239–1.035, p = 0.062)], PFS [HR 0.571 (95% CI 0.311–1.050, p = 0.071)] and OS [HR 0.447 (95% CI 0.168 1.191, p = 0.100)] in patients treated with ICI.

No statistically significant differences were observed for the number of APs during Imin, the lowest current step for AP induction, although there was a clear trend of reduction (decrease by 50% [range 37.5–75]; p = 0.0625; Fig. 2F , green).

transfer of Tregs into the hypothalamus supported a clear trend towards improved glucose tolerance ( P = 0.0643, Fig. 9g ) accompanied by trends toward reduced inflammatory NFκB-related genes in the adipose tissue (Supplementary Fig. 9e ).