“a clear trend”

Despite a clear trend in the univariate analysis, high TLG (≥159.2 g) was not significantly correlated with poor OS (P=0.059).

While the difference in cholangitis was not significant in this analysis, there was a clear trend towards lower cholangitis rates in the PTBS group relative to the EBS group ( p = 0.06).

In the experienced group, a clear trend toward a reduction in anastomotic complications (21.4% vs 5%; p = 0.06) and severe complications (14.3% vs 6.25%; p = 0.27) was observed, although the differences were not significant.

Additionally, a clear trend of increased AUC ∞ /DW (613.46 ± 220.42 h*ng*kg/mL*mg, p = 0.060) and C max /DW (57.69 ± 22.19 ng*kg/mL*mg, p = 0.067) was also observed for SLCO1B1 DFs + PFs in comparison to IFs + NFs (530.36 ± 223.98 h*ng*kg/mL*mg for AUC ∞ /DW; and 49.59 ± 22.09 ng*kg/mL*mg for C max /DW) ( Table 3 ).

The statistical significance level is not clearly reached here, but a clear trend can be seen ( p = 0.06).

However, upon careful reading, the results of the Italian TSUNAMI RCT were not completely negative, but showed a clear trend towards efficacy ( p = 0.06) of CCP versus standard therapy in the subgroup of patients with milder (and thus earlier) disease.

Although we did not find significant changes in ATAD3 phosphorylation or levels in the present LC–MS/MS analysis, there was a clear trend for a decrease in protein levels in NEK10 KO samples (192/178/203 for NEK10 KO samples and 205/228/245 for Parental cells, p = 0.06; Supplemental Table 1).

The analysis showed a clear trend towards increased protein levels GRP78 in neurons of the SNpc; the content of GRP78 increased 1.4 times ( p = 0.06) 3 h after its administration compared with the control ( Figure S4 ).

Similarly, the ItchyQoLTM questionnaire revealed a clear trend of itch reduction after 6 weeks with 80% of subjects (12/15) noting decreased itch ( P = 0.06) which became significant after 12 weeks of bleach baths, with 100% of subjects noting improvements in itch (Fig. 1 e).

Despite a clear trend in the univariable analysis, a high TMTV was not a statistically significant prognostic factor for OS in the CIT group (HR 2.2, 95%CI 1.0–4.8, p = 0.06).

albicans (partial Spearman P = 0.015, R 2 = 0.57) and a clear trend with Candida genus abundance (partial Spearman P = 0.06, R 2 = 0.46; Fig.

A clear trend (p = 0.061) toward higher arrhythmia scores was also observed in older males than in females of the same age (Fig. 2 g).

Furthermore, there was a clear trend toward longer LRRFS [HR 0.497 (95% CI 0.239–1.035, p = 0.062)], PFS [HR 0.571 (95% CI 0.311–1.050, p = 0.071)] and OS [HR 0.447 (95% CI 0.168 1.191, p = 0.100)] in patients treated with ICI.

No statistically significant differences were observed for the number of APs during Imin, the lowest current step for AP induction, although there was a clear trend of reduction (decrease by 50% [range 37.5–75]; p = 0.0625; Fig. 2F , green).

transfer of Tregs into the hypothalamus supported a clear trend towards improved glucose tolerance ( P = 0.0643, Fig. 9g ) accompanied by trends toward reduced inflammatory NFκB-related genes in the adipose tissue (Supplementary Fig. 9e ).

Moreover, according to the Kaplan-Meier analysis, patients who received adequate antiviral treatment demonstrated a clear trend towards reduced complications, although the log-rank p -value was not statistically significant ( p = 0.065) (Fig. 1 ).

Importantly, anti-PD-1 monotherapy produced a clear trend towards reduced M2 macrophages overall, while failing to reach significance when compared to MOPC21 ( P = 0.0654).

2 ), which was significant ( p = 0.04) In the entire cohort the decrease in ATP, although showing a clear trend, did not reach statistical significance ( p = 0.066), whereas ICD shocks did decrease significantly ( p = 0.028).

Figure 4 demonstrates that compared to the DM group, there was a clear trend towards the inhibition of the expression and phosphorylation of AMPKα in the MICT group ( P =0.066, P =0.056).

The difference in distant lymph node metastasis between SARIFA-positive and SARIFA-negative groups showed a clear trend and just failed to show statistical significance ( p = 0.066).

22 In line with previous data, 23 , 24 we observed decreased total IgE (mean −0.47 fold from baseline, ∗∗ p < 0.01) (Figure 5B ) and specific IgE (Der p1) (mean −0.40 fold from baseline, ∗ p < 0.05) (Figure 5C ) while House Dust Mite (HDM) Der p2‐specific IgE (Figure S1f ) showed a clear trend but did not reach statistical significance ( p = 0.0665).

Although the long-term survival rates suggest a clear trend, with a 3-year survival rate of 12.5 % in the CK7+ group and 75 % in the CK7− group ( p -value = 0.067), the difference is not statistically significant.

Although not reaching statistical levels by 2-way ANOVA (interaction p = 0.10) a clear trend for reduced T3/T4 levels was found in HFS ad lib group compared to NC controls ( p = 0.068) and to HFS TRF ( p = 0.055), comforting the idea of local hypothyroidism ( Figure 6 B).

27 In our study, HBEA was not associated with higher AF detection in the second Holter‐ECG compared with those with NSR, although a clear trend was observed at the 12‐month follow‐up (26% versus 13%, P =0.068).

Interestingly, there was a clear trend suggesting that patients with T-ALL harboring a BCL11B mutation had a higher percentage of CR ( P = .068) and negative MRD ( P = .050), although the data were not yet statistically significant at this point ( Figure 1B ).