There were no significant methylation differences between other tumor sub-groups (MSS/MSI-L) and normal tissue samples ( S8 Fig ) ; however, there was a clear trend of higher levels of MLH1 promoter methylation among rhesus sporadic MSI-H compared to MSS tumors as well as a notorious absence of MLH1 methylation in the only LS tumor tested, which is consistent with human CRC biology.
Moreover, a clear trend of increasing amphetamine levels with longer reported durations of use was observed.
Whereas research-driven HIA ( n = 460) showed a steep increase, step-by-step HIA ( n = 71) did not show a clear trend.
In fact, examining the data based on the residual T after 60 h of simulated growth showed a clear trend with detox improvement being maximum around 1% residual T and dropping to lower values when residual T was much higher or lower ( Figure 5 B).
A clear trend was observed: films with higher FSHAp filler content retained more residue post‐degradation.
Although not statistically significant, there is a clear trend that ADAM9 expression predicts a worse outcome for DSS, where an ADAM9-positive phenotype corresponded to a median DSS of 52.5 months (95% CI 33.1–71.9 months), whereas an ADAM9-negative phenotype did not reach median DSS ( P <0.130) after a follow-up of 76.1 months ( Figure 5D ).
Moreover, despite fluctuations in the data, a clear trend toward a robust antiviral effect of the Cu layer in both dry and wet conditions is visible ( Figure 4 ).
[ 40 ], it is difficult to identify a clear trend regarding the content of phenolic acids in cocoa bean processing.
Although the majority of these differences between the two schemes are not statistically significant (see Table 12 ), the small benefit of S3 (and the fact that S1 rarely beats S3) is still a clear trend in the data, and shows also in the TOTAL results.
Each data point represents one gene ontology, and a clear trend is evident.
However, the SOM results for the following years showed a clear trend in the restrictive direction (cf.
There was a clear trend that the up-regulated levels of GANAB were increased in copy number gains and amplifications, as compared to the shallow deletions and diploid (Fig. 7 A, B).
A clear trend was observed, as expected; EDGs accelerate the rates of reaction (up to ca. 100×), and vice versa, EWGs result in reduced rates ( Figure 1 b).
When considering the ionic liquids [C n C 1 im][NTf 2 ] ( n = 2, 3, 4, 6 or 8) a clear trend can be seen for τ Cy3 against η .
Despite this limitation, a clear trend is observed with advanced stages of fibrosis tending to yield more accurate results.
There was a clear trend of increase in gait speed and stride length across the 10 treatment sessions in the active tDCS group, with significant measurable differences by the fourth treatment session.
Turning to the perovskites obtained from the five sequential scaffold stacks, a clear trend emerges.
Among the top five regions, colorectal cancer caused by alcohol abuse factors and high body mass index tends to show a clear trend of increasing age ( Supplementary Figures S1B-D, S2B-D ).
Mice homozygous for the vI56i mutation showed results similar to those of I56i (–/–) mutants with a clear trend for increased socialization that did not reach statistical significance ( Figure 6B ).
While these measures are calculated as a fraction, their development over time shows a clear trend and indicates non-stationarity.
As the Malawi HIV programme raised the CD4 thresholds for ART eligibility from 250 to 350 cells/μL in 2011 to 500 cells/μl in 2014 13 , 18 , 19 , a clear trend in declining annual TB rates among ART patients was observed between 2008 and 2014.
However, there was a clear trend towards overexpression of TM4SF1 and IGFBP3 in patients with poor outcome.
Correlating the donor age to the predicted biological age of the cell populations revealed a clear trend, which justifies applying the ex vivo developed age clocks to cell culture samples, particularly to identify relative changes after treatment ( Supplementary Figure S6 ).
However, for other microorganism pairs a clear trend was not observed.
Melt Flow Index The melt flow index measurements revealed a clear trend of increasing fluidity with the addition of post-consumer recycled polypropylene to virgin polypropylene.