Stratified analysis of euploidy rates based on different morphological grades and embryonic days showed a decreasing trend in euploid + balanced rates from good (AA, AB, BA) to fair (BB) to poor (BC, CB, AC, CA, CC) embryos (PGT-A group: 53.0% vs. 47.8% vs. 40.0%, p = 0.001; PGT-SR group: 38.3% vs. 31.7% vs. 28.6%, p = 0.001).
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In the GCF samples of periodontitis patients, the level of miR-205-5p revealed a decreasing trend, contrary to the trend of NEAT1 ( Fig. 4 C, P < 0.001).
Overall, 500 students (48.4%) were at risk of clinical depression with a decreasing trend over academic years (59.3% in Year 1 to 35.5% in Year 6, p<0.001, see eTable 1 in the online supplemental material ).
There was a decreasing trend in OS and CSS median survival as the degree of tumor-related features increased in the T, N, grade, and tumor size variables (p < 0.001, see Supplementary Figures 1–7 ).
Conversely, predominantly cystic tumours are strongly correlated with SPCs, with a decreasing trend of occurrence as the tumour becomes more solid ( Figure 7 ) ( p < 0.001).
pneumoniae strains, with a decreasing trend during the four semesters ( p -value < 0.001), which presented an 80% resistance rate to ampicillin/sulbactam and 73.33% to ciprofloxacin.
Piecewise regression estimates provide no evidence of a time trend between 2000 and 2012 (PRR 1.00, 95% CI 0.99, 1.02; p = 0.99), whereas there was an increasing trend in TB prevalence of DS between 2013 and 2015 (PRR 1.16, 95% CI 1.07, 1.26; p < 0.001) and a decreasing trend between 2016 and 2021 (PRR = 0.94, 95% CI 0.92, 0.97; p < 0.001) ( Fig. 2 , Table 2 ).
The pH of the fish cakes was 7.09 in the control group and 6.87–7.04 in the garlic-powder groups, demonstrating a decreasing trend with increasing amounts of garlic powder (P < 0.001).
Results During the study period, altogether 19 550 DEs were reported, and the annual number of error reports showed a decreasing trend ( n = 3 913 in 2015 vs. n = 2 117 in 2020, RR 0.54, p < 0.001).
A decreasing trend in mortality was observed in both the groups (CAI: -0.53%/year and NI: -0.72%/year, P < 0.001).
3 Results 3.1 HR A decreasing trend was observed in the control group (Time effect: F (7, 231) = 4.583, p < 0.001, η 2 = 0.122).
BMI was significantly different among the three groups of nutritional status with a decreasing trend from normal to malnourished group ( P < 0.001).
Worldwide, a decreasing trend and significant associations between the ASPR and the SDI ( R = −0.22, p =0.0013) and between the ASDR and the SDI ( R = −0.28, p < 0.001) were observed.
Treatment with GEO and citral caused a decreasing trend in plasma cholesterol and LDL-C levels in ApoE −/− mice compared with the GC group; moreover, high-dose GEO and citral increased plasma HDL-C levels ( p = 0.0015 and p = 0.0054, respectively).
PC exhibited a decreasing trend with an increase in the BMD quartile (Q1: 242.55 ± 56.12; Q2: 243.75 ± 58.61; Q3: 243.20 ± 58.40; Q4: 238.38 ± 56.79; P = 0.0017).
They showed a decreasing trend and a failing significance for the vocal tic and a non-significant change for the OCD subscores (motor: F 1,10 = 17.500, p = 0.0019, vocal: F 1,10 = 4.865, p = 0.0519, OCD: F 1,10 = 0.129, p = 0.7287 for the respective subscores).
2 ) but remaining at the lower end of the overall copy numbers (0.05–0.2 copies/μl) and showing no significant pattern of eDNA signal accumulation over time except a decreasing trend for nylon, highly influenced by the high initial copy numbers ( p ≤ 0.0019, Fig. 3 ).
Figure 1 (a) shows that there were no changes in overall adherence over time ( P = 0.108) and adherence in ED-PrEP users ( P = 0.270), whereas D-PrEP users showed a decreasing trend (from 78% in the first follow-up to 73.1% after 12 months, P = 0.002).
The results exhibit a decreasing trend of pH over 180 days for all samples, as indicated by the significant time effect on the pH ( P = .002) based on the GEE model with adjustment for the effect of the product on pH.
Among all age groups, the highest monoresistance was for INH (1.2%), and across age groups, only INH monoresistance showed a decreasing trend with age ( P = .002).
Besides, when the stroma was denser (TSR < 1), E-cadherin expression showed a decreasing trend, exhibiting a significant statistical significance ( P = 0.002) (Supplementary Table 1).
Then, in AT8, there was a decreasing trend in the ALP level after training cessation (104.1 U/L, 95% CI) at T12; the value is significantly ( p = 0.002) lower than the baseline value.
In both moderate and severe groups, condylar volume and superficial area showed a decreasing trend from T 0 to T 1 (moderate: P = 0.002, P = 0.001; severe: P = 0.001, P = 0.003), and no difference was found between T 1 to T 2 .
The mutation frequencies of BRCA2 and TP53 , as well as the TMB, were higher in the response group ( P = 0.002, 0.042, 0.072, respectively) and demonstrated a decreasing trend across the response status ( P = 0.002, 0.067, 0.008, respectively; Fig. 2 B–D).
The ammonia levels showed a decreasing trend over time ( P = 0.002).