“a decreasing trend”

Treatment with GEO and citral caused a decreasing trend in plasma cholesterol and LDL-C levels in ApoE −/− mice compared with the GC group; moreover, high-dose GEO and citral increased plasma HDL-C levels ( p = 0.0015 and p = 0.0054, respectively).

PC exhibited a decreasing trend with an increase in the BMD quartile (Q1: 242.55 ± 56.12; Q2: 243.75 ± 58.61; Q3: 243.20 ± 58.40; Q4: 238.38 ± 56.79; P = 0.0017).

They showed a decreasing trend and a failing significance for the vocal tic and a non-significant change for the OCD subscores (motor: F 1,10 = 17.500, p = 0.0019, vocal: F 1,10 = 4.865, p = 0.0519, OCD: F 1,10 = 0.129, p = 0.7287 for the respective subscores).

2 ) but remaining at the lower end of the overall copy numbers (0.05–0.2 copies/μl) and showing no significant pattern of eDNA signal accumulation over time except a decreasing trend for nylon, highly influenced by the high initial copy numbers ( p ≤ 0.0019, Fig. 3 ).

The results exhibit a decreasing trend of pH over 180 days for all samples, as indicated by the significant time effect on the pH ( P = .002) based on the GEE model with adjustment for the effect of the product on pH.

Among all age groups, the highest monoresistance was for INH (1.2%), and across age groups, only INH monoresistance showed a decreasing trend with age ( P = .002).

Furthermore, a decreasing trend in CRHp prevalence was noted for the European continent (25% in 2013–2016 to 20% (2017–2020), p = 0.002) [ 23 ].

Then, in AT8, there was a decreasing trend in the ALP level after training cessation (104.1 U/L, 95% CI) at T12; the value is significantly ( p = 0.002) lower than the baseline value.

In both moderate and severe groups, condylar volume and superficial area showed a decreasing trend from T 0 to T 1 (moderate: P = 0.002, P = 0.001; severe: P = 0.001, P = 0.003), and no difference was found between T 1 to T 2 .

Figure 1 (a) shows that there were no changes in overall adherence over time ( P = 0.108) and adherence in ED-PrEP users ( P = 0.270), whereas D-PrEP users showed a decreasing trend (from 78% in the first follow-up to 73.1% after 12 months, P = 0.002).

Besides, when the stroma was denser (TSR < 1), E-cadherin expression showed a decreasing trend, exhibiting a significant statistical significance ( P = 0.002) (Supplementary Table 1).

The mutation frequencies of BRCA2 and TP53 , as well as the TMB, were higher in the response group ( P = 0.002, 0.042, 0.072, respectively) and demonstrated a decreasing trend across the response status ( P = 0.002, 0.067, 0.008, respectively; Fig. 2 B–D).

The ammonia levels showed a decreasing trend over time ( P = 0.002).

Before biosimilars were introduced, originator infliximab prices presented a decreasing trend in Australia ( P = 0.002), Canada ( P < 0.001), India ( P < 0.001), Japan ( P < 0.001), and Korea ( P < 0.001).

Trend analysis of the PM 10 dataset showed a decreasing trend (Modified M–K Hamed Rao approach test result: tau ( τ ) = − 0.3, p -value = 0.002) with a low rate of 0.2 μg m −3 per annum during 2018–2020 (Fig. 5 ).

Episodes portraying ARAs showed a decreasing trend over time, with more episodes featuring ARAs in the programme’s earlier years (20 episodes, 12.9%) versus the latter half (3 episodes, 2.4%, P = 0.002).

In contrast, MCDK shows a decreasing trend in Least Squares mean differences, with a significant negative difference at GA 32 ( p = 0.002), but no significant differences at 4 weeks postnatally ( p = 0.42) or at 2 years of age ( p = 0.88), suggesting that the impact diminishes over time.

Calcifications vary by pathological stage Both lattice parameters (‘a’ and ‘c’ axes) for HAP showed a decreasing trend with increasing pathological stage, with a significant weak negative correlation between the ‘c’ axis and pathological stage (r τ = − 0.284, p = 2.17 × 10 –3 ) (Fig. 4 a,b).

Poisson regression indicated an increasing trend in THA and labral repair (P < 0.0001, P = 0.0033) and a decreasing trend in pelvic osteotomy, femoral osteotomy, and synovectomy (P = 0.0024, P < 0.0001, P < 0.0001).

While BLI detected tumors at 1-week, it failed to detect tumor growth, displayed a decreasing trend overtime (slope = -9.0x10 8 ; p = 0.0028), and terminal signal did not correlate with ex vivo tumor mass (r = 0.01853; p = 0.6286).

Briefly, VTI QRS-3D showed a decreasing trend across age groups from 18 to 65 years ( p = 0.003 for females, p < 0.0001 for males).

A decreasing trend was observed in all regions except West which showed an increase with AAPC of 0.38 (95% CI, 0.15 to 0.62, p=0.003).

Additionally, CVI showed a decreasing trend in eyes with early-stage AMD, with a statistically significant reduction in the nasal sector ( P = 0.003) ( Table 4 ).

The Friedman test revealed a decreasing trend over time (from M0 to M12) in scores on sleep disorders ( P = 0.003, Figure 2 and Table 2 ) and anxiety ( P = 0.0001, Figure 2 and Table 2 ).

The trend slope changed in a decreasing manner (− 0.798, 95% CI − 1.233 to − 0.363, p-value = 0.001), resulting in a decreasing trend of − 0.622 cases (p-value = 0.003).