“a decreasing trend”

The inhibitory effect of anti-rTsSPc antibody was antibody dose-dependent ( r = 0.967, P < 0.01), and exhibited a decreasing trend with increasing of serum dilution ( F = 1797.671, P < 0.0001) ( Fig 16E ).

Whereas all the other groups showed a decreasing trend in comparison to the diabetic group with adjusted ( p < 0.0001****).

Urinary pathogens showed a decreasing trend for nitrofurantoin (from 17% to 7%, p=0.0001).

The incidence rate showed a rapidly increasing trend from 1975 to 1987, with an APC of 3.3% (95% confidence interval [CI] = 2.8–3.9%, P < 0.0001), while this increase slowed from 1988 to 2001 (APC = 0.8%, 95% CI = 0.4–1.1%, P < 0.0001), and was followed by a decreasing trend from 2002 to 2016 (APC= −0.7%, 95% CI= −0.9% to −0.5%, P < 0.0001).

Additionally, Cumulative Forest Plot showed a decreasing trend in the prevalence of Aeromonas infection in children with diarrhoea over time ( P = 0.0001).

However, the BMI of women without disability indicated a rising trend and that of women with disability indicated a decreasing trend ( P < .0001).

Among functional echocardiographic parameters, E/A ratio (p < 0.0001) showed a decreasing trend, whereas E/e’ ratio increased (p < 0.0001) with age.

However, there was a change in pattern of incidence for some case types over time with preterm rupture of membrane, preeclampsia, and preterm labour showing a decreasing trend (p-values < 0.0001) and fetal anomaly showing an increasing trend (p-values < 0.0001).

IHM rates also varied between regions, increasing in all but the southeast, which showed a decreasing trend (y = -0.1122x + 4.427; R 2 = 0,728; P < 0.0001).

Prevalence and trend of TTIs in blood donors according to donor status The analysis of first-time donors (who comprised 23.3% of all donors) showed a decreasing trend in the prevalence of HBV ( P < 0.0001, R: -0.98), HIV ( P < 0.18, R: -0.49), HCV ( P < 0.0001, R: − 0.98) and HTLV 1/2 ( P < 0.0001, R: − 0.95) from 2010 to 2018.

Striking features of this record includes a decreasing trend of −0.0015 ± 0.0002 pH year −1 from AD 1838–2001 (R 2 = 0.63, p < 0.0001) and inter-decadal variations with amplitudes of 0.1–0.2 units ( Fig. 2b ).

Total white blood cell count showed a decreasing trend across tertiles: 7.0 × 10 9 /L in T1, 6.7 × 10 9 /L in T2, and 5.5 × 10 9 /L in T3 ( p < 0.0001).

The main effect of time was significant and there was a decreasing trend in LEDD (estimate = − 48.8, SE = 8.4, p < 0.0001).

In terms of the severity of SCI, there was a decreasing trend over time for AIS grade A (P = 0.0036) and grade C (P < 0.0001), while an increasing trend was observed for grade D (P < 0.0001).

We observed a decreasing trend of unintended pregnancy (52.2%-30.2% among non-IDUs, 65.8%-46.0% among IDUs, both P < 0.0001).

Tests of the year main effect revealed a decreasing trend for wrist ( p <.0001), an increasing trend for vertebral ( p =.0012), and no statistically significant change for humerus ( p =.2226).

Pairwise reduction curves showed a decreasing trend on transitioning from Serotype I to II ( P < 0.0001) in 34/48 (70.8%) samples, from Serotype I to III ( P = 0.0281) in 30/48 (62.5%) samples, and from Serotype I to IV ( P < 0.0001) in 38/48 (79.2%) samples ( Figure 5 (C)).

Additionally, we noted the levels of hematocrit (HCT) increased significantly over time after infection with a mean count of 31.6, 35.3 (p = 0.0001) and 37.7 (p<0.0001) % at 1, 2, and 3 d.p.i., respectively, when compared to 29.2% in uninfected mice ( Fig 3K ).Thrombocyte (PLT) counts showed a decreasing trend, albeit insignificant, at the early phase of infection, that gradually rebound to thrombocytosis at the peak of infection with a mean count of 952 K/uL (p<0.0001) at day 3 p.i., when compared to those measured before infection with a mean count of 484 K/uL ( Fig 3E ).

Furthermore, Treg populations showed a decreasing trend in the untreated and/or vehicle groups but an obvious increase after ERC-CM treatment (ERC-CM group vs. untreated group, p < 0.0001; ERC-CM group vs. vehicle group, p < 0.0001) (Figures 4(b) and 4(e) ).

The common tumor-related symptoms were pain, fatigue and anorexia, from which 31.7, 22.2 and 14.8% of the patients suffered at baseline, but the proportions decreased to 8.6, 5.9 and 3.7%, respectively, at 24 weeks after the treatment in a time-dependent manner with a decreasing trend ( P < 0.0001).

In the total population, no significant trend could be observed in the T2DM group [APC: −0.50% (−1.12–0.10%), p = 0.0991], while a decreasing trend was found in the Non-Diab group [APC: −1.79% (−2.07–−1.52%), p < 0.0001].

25.22 ± 3.58 kg) exhibited the same trend as BF and increased progressively across the BMI categories ( p < 0.0001), LM% revealed a decreasing trend, with normal-weight older adult males demonstrating the highest LM% (71.06 ± 6.73%), followed by overweight (64.35 ± 4.82%) then obese (59.66 ± 4.07%) ( p < 0.0001) individuals.

However, as the clinical stage advanced, both the SDNN and RMSSD displayed a decreasing trend ( P < 0.0001).

Estimates for the main effect of time revealed a decreasing trend ( p < 0.0001) in both models.

For women, only patients <65 years showed a decreasing trend (β = −32.3, P < 0.0001).